Cobalt-Mediated Syntheses of Molecules of Theoretical and Synthetic Importance

这项研究的重点是使用过渡金属组装高能量的炔烃前体，然后进行寡环化和随后的转化，从而制备苯系物。苯具有线形、角形、C3对称、圆形、弯曲和“之”字形拓扑结构，因此具有显著的物理和化学性质。目前项目的目标包括研究苯类的化学，特别是：剖析pi和sigma电子对应变的贡献；建立氧化还原、电荷转移和自组装行为，以发现苯类作为磁性和电子器件的基础材料的潜力；研究基本的有机金属反应和单分子热异构化；制备系列中的新成员并朝着更大的独特碳网络进展；构建理论上重要的碳氢化合物；并将该系列扩大到包括杂环类似物。有了这个续展奖项，有机和高分子化学计划将支持加州大学伯克利分校化学系的K.Peter C.Vollhardt博士的研究。沃尔哈特教授将把他的工作重点放在利用过渡金属介导的转化来合成一些高能和具有拓扑学意义的苯系烃。这项研究有可能对磁性和导电材料领域产生影响，它也是研究生和博士后学员教育的极好培训基地。

The focus of this research is the use of transition metals to assemble highly energetic alkyne precursors which are then subjected to oligocyclizations and subsequent transformations which result in the preparation of phenylenes. The phenylenes have linear, angular, C3-symmetric, circular, bent and "zigzag" topologies and, thus, remarkable physical and chemical properties. The goals of the current project include the investigation of the chemistry of the phenylenes, in particular: to dissect pi and sigma electronic contributions to strain; to establish redox, charge transfer and self assembly behavior to discover the potential of phenylenes for use as building blocks for magnetic and electronic devices; to investigate fundamental organometallic reactions and unimolecular thermal isomerizations; to prepare novel members in the series and to progress towards larger unique carbon networks; to construct theoretically important hydrocarbons; and to expand the series to include heterocyclic analogs.With this renewal award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. K. Peter C. Vollhardt of the Department of Chemistry at the University of California, Berkeley. Professor Vollhardt will focus his work on the use of transition metal mediated transformations for the synthesis of a number of highly energetic and topologically interesting benzenoid hydrocarbons. The research has the potential to exert an impact on the area of magnetic and conducting materials and it also serves as an excellent training ground for the education of graduate students and postdoctoral participants.