Meiotic Drive and Sexual Selection in Diopsid Dipterans

双翅目减数分裂驱动和性选择

• 批准号: 0077878
• 负责人: Gerald Wilkinson
• 金额: $ 32.4万
• 依托单位: University of Maryland, College Park
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2004-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0077878&HistoricalAwards=false
• 关键词: Meiotic; Drive; Sexual; Selection; Diopsid

0077878WilkinsonThis project aims to test the hypothesis that females choose ornamented males to alter the sex ratio of their progeny. Two species of stalk-eyed flies (family Diopsidae) that exhibit sexual dimorphism for eye stalk length and X-linked meiotic drive (i.e., sperm bearing Y-chromosomes fail to develop) will be used to test three predictions of this hypothesis. To determine the location of genes that influence eye span and meiotic drive, a quantitative trait locus (QTL) study will be conducted with arbitrary genetic markers. To determine how selection maintains meiotic drive in the population, the longevity of males and females, the fecundity of females, and sperm depletion by males that do or do not carry drive alleles will be compared. To determine if correlated evolution between eye span and drive has occurred, progeny sex ratio, male morphology and sperm development will be assayed for nine populations of flies recently captured from southeast Asia.This project is unique and important because it tests an explicit genetic mechanism for adaptive mate choice. In addition, a genetic linkage map for a non-standard model organism will be developed and may provide novel insights on genome evolution. Finally, comparison to other meiotic drive systems may reveal if sex chromosome transmission can be altered in multiple ways, thereby providing a potential biocontrol mechanism.

威尔金森这个项目的目的是验证一种假设，即雌性选择有装饰的雄性来改变其后代的性别比例。两种茎眼苍蝇(Diopsidae科)在眼柄长度和X连锁减数分裂驱动(即携带Y染色体的精子无法发育)方面表现出性别二型性，将被用来检验这一假说的三个预测。为了确定影响眼距和减数分裂驱动的基因的位置，将使用任意的遗传标记进行数量性状基因座(QTL)研究。为了确定选择如何维持种群中的减数分裂动力，将比较雄性和雌性的寿命、雌性的繁殖力以及携带或不携带驱动等位基因的雄性的精子耗竭。为了确定眼距和驱动力之间是否发生了相关的进化，将对最近从东南亚捕获的9个果蝇种群的后代性别比例、雄性形态和精子发育进行分析。这个项目是独一无二的，也是重要的，因为它测试了适应配偶选择的明确遗传机制。此外，还将开发非标准模式生物的遗传连锁图谱，并可能为基因组进化提供新的见解。最后，与其他减数分裂驱动系统的比较可能揭示性染色体传递是否可以以多种方式改变，从而提供一种潜在的生物控制机制。