Multi-scale Mechanics Analysis of Bone Remodeling in Normal vs. Osteoporotic Trabecular Bone

点击翻译按钮获取中文摘要

0085137We will address remodeling in trabecular bone from a mechanical viewpoint. In order to understand how mechanical factors contribute to this process we will predict local stress and strain fields at the cellular level where bone remodeling takes place. In particular we are interested in differences between healthy and osteoporotic bones. By knowing local fields in these two types of bone, under the same external loads, we hope to determine relations between mechanical load and bone remodeling in healthy and osteoporotic bone. Our analysis will account for the hierarchical nature of bone and will involve both theory and experiments.