Beyond Proteomics: structure and function of protein modifications

超越蛋白质组学：蛋白质修饰的结构和功能

• 批准号: LE100100150
• 负责人: Prof Nicolle Packer
• 金额: $ 33.34万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE100100150
• 关键词: Beyond; Proteomics; structure; function; protein

The world's leading cancer therapeutics have come from the protein phosphorylation field, and glycomics has led to drugs that combat the flu and that stimulate red blood cell production in cancer patients. Thus there is a bright future for discovery of new medicines based on new knowledge in this area. Protein modifications are key to the understanding of disease mechanisms and for searching for new disease markers and new therapeutics. In the hands of local experts the instruments will enable identification of these modifications and provide improved understanding of biology, increase the national competitiveness of Australia's scientists, and provide advanced technology training to the next generation of scientists.

世界领先的癌症治疗方法来自蛋白质磷酸化领域，糖组学已经导致对抗流感和刺激癌症患者红细胞生成的药物。 因此，在这一领域的新知识的基础上发现新的药物有一个光明的前景。 蛋白质修饰是理解疾病机制和寻找新的疾病标志物和新疗法的关键。 在当地专家的手中，这些仪器将能够识别这些修改，并提供更好的生物学理解，提高澳大利亚科学家的国家竞争力，并为下一代科学家提供先进的技术培训。