Future Industries Research - Biotechnology and Nanotechnology: Small talk: Communication networks in microbes

未来产业研究 - 生物技术和纳米技术：闲聊：微生物中的通信网络

• 批准号: FS110200026
• 负责人: Prof Nicolle Packer
• 金额: $ 35.18万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Super Science Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-12-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FS110200026
• 关键词: Future; Industries; Research; Biotechnology; Nanotechnology

We will use the Australian Proteome Analysis Facility to address the multifaceted mechanisms of microbial interactions and produce new knowledge about the pathogen Pseudomonas aeruginosa, a common cause of death in cystic fibrosis patients. We will characterise the interactions between P. aeruginosa and the emerging fungal pathogen Scedosporium aurantiacum as a proactive step towards better understanding of pathogen communication. Improved understanding of pathogen interactions should facilitate the development of novel anti-adhesives as therapeutics. Our project will train young scientists in a new integrated approach to biology.

我们将利用澳大利亚蛋白质组分析设施来解决微生物相互作用的多方面机制，并产生有关病原体铜绿假单胞菌的新知识，铜绿假单胞菌是囊性纤维化患者的常见死因。我们将描述铜绿假单胞菌和新兴真菌病原体金黄色Scedosporium aurantiacum之间的相互作用，作为更好地了解病原体通讯的主动步骤。提高对病原体相互作用的了解应有助于开发新型抗粘连剂作为治疗剂。我们的项目将培训年轻科学家采用新的综合生物学方法。