Acquisition of an LC Ion-Trap Mass Spectrometer for Interdisciplinary Chemical Analysis

凭借化学研究仪器和设施（CRIF）计划的这一奖项，伦斯勒理工学院化学系将获得用于跨学科化学分析的LC离子阱质谱仪。这一设备将加强若干领域的研究，其中包括：（a）肽的排序和合成小分子蛋白质辅助因子的特性;（B）在粘土上合成的寡核苷酸的分离和鉴定;（c）前列腺素和白三烯的分离和用硝酮自旋捕集器捕获的自由基的鉴定;（d）湖泊和河流表面微层的分析;（e）组合生物催化剂的结构说明;和f）光降解环境污染物的结构测定。 质谱（MS）是一种用于探测紧密结构细节并获得大量有机、生物有机和有机金属分子的分子组成的技术。这些研究的结果将对包括生物技术和环境化学在内的许多领域产生影响。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Rensselaer Polytechnic Institute will acquire an LC Ion-Trap Mass Spectrometer for Interdisciplinary Chemical Analysis. This equipment will enhance research in a number of areas including a) the sequencing of peptides and characterization of synthetic small-molecule protein cofactors; b) separation and identification of oligonucleotides synthesized on clay; c) prostaglandin and leukotriene separations and identification of free radicals trapped with nitrone spin traps; d) analysis of lake and river surface microlayers; e) structural elucidation of combinatorial biocatalysts; and f) structure determination of photodegraded environmental pollutants. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The results from these studies will have an impact in a number of areas including biotechnology and environmental chemistry.