Acquisition of an LC Ion-Trap Mass Spectrometer for Interdisciplinary Chemical Analysis

购买用于跨学科化学分析的 LC 离子阱质谱仪

• 批准号: 0091892
• 负责人: Thomas Apple
• 金额: $ 15.73万
• 依托单位: Rensselaer Polytechnic Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-15 至 2004-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0091892&HistoricalAwards=false
• 关键词: Acquisition; LC; Ion; Trap; Mass

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Rensselaer Polytechnic Institute will acquire an LC Ion-Trap Mass Spectrometer for Interdisciplinary Chemical Analysis. This equipment will enhance research in a number of areas including a) the sequencing of peptides and characterization of synthetic small-molecule protein cofactors; b) separation and identification of oligonucleotides synthesized on clay; c) prostaglandin and leukotriene separations and identification of free radicals trapped with nitrone spin traps; d) analysis of lake and river surface microlayers; e) structural elucidation of combinatorial biocatalysts; and f) structure determination of photodegraded environmental pollutants. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The results from these studies will have an impact in a number of areas including biotechnology and environmental chemistry.

通过化学研究仪器和设施（CRIF）项目的奖励，伦斯勒理工学院化学系将获得一台用于跨学科化学分析的LC离子阱质谱仪。该设备将加强许多领域的研究，包括a)肽的测序和合成小分子蛋白质辅助因子的表征；B)粘土合成寡核苷酸的分离与鉴定；C)前列腺素和白三烯的分离和用硝基自旋阱捕获自由基的鉴定；D)湖泊和河流表面微层分析；E)组合生物催化剂的结构解析；f)光降解环境污染物的结构测定。质谱（MS）是一种用于探测内部结构细节和获得大量有机、生物有机和有机金属分子的分子组成的技术。这些研究的结果将对包括生物技术和环境化学在内的许多领域产生影响。