Infrared Matrix-assisted Laser Desorption/Ionization Mass Spectrometry

授予埃默里大学Kermit Murray教授的这项题为“红外基质辅助激光解吸/电离质谱法（IR-MALDI）”的奖项得到了分析和表面化学项目的支持。 研究的目标是解决IR-MALDI理解中的基本问题。 研究将研究阈值注量、离子产额和平均初始离子速度与波长的关系。 研究人员将利用独特的双脉冲激光实验提供更多的信息和更好地区分解吸和电离过程。 此外，该研究将包括新的应用，如组织显微切割结合IR-MALDI和使用冰基质的非共价复合物的研究。主要研究者通过他广泛可用的互联网资源为社区做出了贡献。这项研究有可能在分子和细胞生物学以及质谱领域产生重大影响。

This award to Professor Kermit Murray of Emory University entitled "Infrared Matrix-assisted Laser Desorption/Ionization Mass Spectrometry (IR-MALDI)" is supported by the Analytical and Surface Chemistry Program. The goals of the research are to address fundamental problems in the understanding of IR-MALDI. The research will study wavelength dependence of threshold fluences, ion yields and average initial ion velocities. The investigator will utilize unique two-pulse laser experiments to provide more information and better differentiation between the desorption and ionization processes. In addition the research will include novel applicationssuch as tissue microdissection in conjunction with IR-MALDI and the use of ice matricies for the study of non-covalent complexes.The principle investigator is recognized for his contributions to the community through his widely available internet resources. This research has the potential for high impact in the areas of molecular and cellular biology, as well as, in mass spectrometry.