Electrochemical and Chemical Generation of Reactive Organic Species

本研究考察了短命活性中间体的生成和合成应用，包括1，3-偶极、邻氨基二甲烷、α-酮基碳正离子、β-三甲基硅基和β-烷氧基取代碳正离子。将利用电化学和化学方法来生成中间体。使用微乳液和/或离子液体作为有机电化学反应的介质可能被证明比传统溶剂具有优势。此外，如果从这项研究中实现新的“绿色”电化学方法，将对社会产生潜在的好处。有了这个续展奖，有机化学和高分子化学计划正在支持卫斯理大学化学系的阿尔伯特·J·弗莱教授的研究。弗莱教授的研究调查了一些短命有机中间体的生成和反应活性。特别是，拟议的电催化再生碘化氢作为还原剂和电催化氧化有可能导致新的环境友好型反应的发展。这些反应可能成为对环境友好和高效的新工业过程。

This research investigates the generation and synthetic applications of short-lived reactive intermediates, including 1,3-dipoles, ortho-quinodimethanes, alpha-keto carbocations, beta-trimethylsilyl- and beta-alkoxy-substituted carbocations. Both electrochemical and chemical means will be utilized to generate the intermediates. The use of microemulsions and/or ionic liquids may prove to have advantages over classical solvents as media for organic electrochemical reactions. In addition, there is a potential benefit to society if new "green" electrochemical methods are realized from this research.With this renewal award, the Organic and Macromolecular Chemistry Program is supporting the research of Professor Albert J. Fry in the Department of Chemistry at Wesleyan University. Professor Fry's research investigates the generation and reactivity of a number of short-lived organic intermediates. In particular, the proposed electrocatalytic regeneration of hydrogen iodide as a reducing agent and the electrocatalytic oxidation has the potential to lead to the development of new, environmentally friendly reactions. These reactions could become new environmentally benign and efficient industrial processes.