Modeling the Chemistry of the Nitrite and Sulfite Reductases

亚硝酸盐和亚硫酸盐还原酶的化学建模

• 批准号: 0100774
• 负责人: Patrick Farmer
• 金额: $ 33万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-01 至 2004-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0100774&HistoricalAwards=false
• 关键词: Modeling; Chemistry; Nitrite; Sulfite; Reductases

Dr. Patrick J. Farmer of the Department of Chemistry, University of California at Irvine, is supported by the Inorganic, Bioinorganic and Organometallic Chemistry program of the Chemistry Division, National Science Foundation, for his work on modeling the chemistry of heme-based nitrite and sulfite reductases. The various enzymes perform integral steps in the biochemical cycling of nitrogen and sulfur, which are of importance in the global denitrification of soil fertilizers and in the removal of oxides of nitrogen and sulfur, which are pollutants from industrial waste-waters.The studies will have implications for the global effects of modern agriculture, based on understanding the chemical basis for the generation of non-carbon greenhouse gases. The studies will provide a diverse group of undergraduate and graduate students (some are Asian, Hispanic or from Eastern European countries) with invaluable experience that will be relevant to the American economy, and will form the training ground for the next generation of scientists.

加州大学欧文分校化学系的帕特里克·J·法默博士因其在血红素亚硝酸盐和亚硫酸盐还原酶化学建模方面的工作而得到国家科学基金会化学部无机、生物无机和有机化学项目的支持。各种酶在氮和硫的生物化学循环中起着不可或缺的作用，这对全球土壤肥料的脱氮和去除氮和硫的氧化物（工业废水中的污染物）至关重要。这些研究将在理解非碳温室气体产生的化学基础的基础上，对现代农业的全球影响产生影响。这些研究将为本科生和研究生（有些是亚洲人，西班牙裔或来自东欧国家）提供与美国经济相关的宝贵经验，并将成为下一代科学家的培训基地。