Support of The Interface Of Three Areas OF Biomedical Science With The Mathematical Sciences

通过数学和统计方法，我们有很多机会增加对生物学和生物医学研究挑战的理解。但是，由于历史上学科之间的鸿沟，研究人员在这些主题上进行合作并不容易。为了克服这一鸿沟，国家研究委员会的数学科学委员会与NRC的生命科学委员会合作，举办了一个研讨会，涉及各个学科的大约70人，(1)在现场激发一些新的合作和见解；(2)向数学科学家介绍一些数学研究方向（通过印刷品和互联网传播），这些方向有助于生物和生物医学科学中重要的正在进行的研究。在研讨会上，细胞功能动力学建模、疾病状态建模和神经科学领域的主要研究人员描述了各自领域的一些主要研究挑战。他们不局限于“数学”挑战；研讨会讨论的重点是确定应该进行的数学和统计研究，以推进生物学和生物医学研究议程。通过广泛的数学科学家参与，研讨会带来了许多不同的观点和想法，以解决演示中提出的开放性问题。其目的是激发广泛的讨论，提炼出最好的想法。研讨会的总结将广泛传播，以便让更多的数学科学家了解从事生物学和生物医学研究所需的基本知识。

Weidman0109132 There are tremendous opportunities to increase ourunderstanding of biological and biomedical research challengesthrough mathematical and statistical methods. But it is not easyfor researchers to collaborate on these topics because of ahistorical gulf that separates the disciplines. In order toovercome that gulf, the Board on Mathematical Sciences of theNational Research Council, in collaboration with the NRC's Boardon Life Sciences, holds a workshop, involving some 70 peopleacross the disciplines, to (1) stimulate some new collaborationsand insights on the spot and (2) provide an introduction formathematical scientists (disseminated via print and the Internet)of some mathematical research directions that contribute toimportant ongoing research in the biological and biomedicalsciences. At the workshop, leading researchers in dynamical modelingof cellular functions, in modeling of disease states, and inneuroscience describe some of the major research challenges intheir fields. They do not limit themselves to "mathematical"challenges; workshop discussions are focused on identifying themathematical and statistical research that should be undertakenin order to advance the biological and biomedical researchagendas. By involving a broad range of mathematical scientists,the workshop brings a number of different perspectives and ideasto bear on the open questions raised by the presentations. Theaim is to stimulate a wide-ranging discussion and distill out thebest ideas. The workshop's summary will be widely disseminatedin order to give many more mathematical scientists the basicunderstanding needed to become engaged in biological andbiomedical research.