RUI: Chemistry at the Interface Between Computation and Experiment: Chiral Recognition using Novel Organometallic Complexes

威尔明顿的北卡罗来纳州大学化学系的大卫·P·白色（David P. White）因其在有机金属配合物的手性识别方面的工作而获得无机、生物无机和有机金属化学项目的支持。该项目结合了分子建模，计算和合成方法，以更好地了解立体选择性的前手性烯烃结合[（eta-5-C5 H4 R）Re（CO）（L）（NO）]+配合物（R = Me，t-Bu，SiMe 3，CPh 3; L=PMe3、PMe2Ph、PMePh2，该奖项是根据本科院校研究计划（RUI）颁发的。并强调在合成和计算的互补工具的本科研究人员的培训。这一工作取代的手性配合物的ESTA也可能导致更好的路线烯烃的对映选择性氢化和其他手性转化。

David P. White, Chemistry Department, University of North Carolina at Wilmington, is supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program for his work on chiral recognition by organometallic complexes. The project incorporates molecular modeling, computational and synthetic approaches to better understand stereoselective prochiral olefin binding to [(eta-5-C5H4R)Re(CO)(L)(NO)]+ complexes (R = Me, t-Bu, SiMe3, CPh3; L=PMe3, PMe2Ph, PMePh2, PPh3).This award is made under the Research at Undergraduate Institutions Program (RUI) and emphasizes the training of undergraduate researchers in the complementary tools of synthesis and computation. This work on substituted cyclopentadienyl complexes of rhenium may also lead to better routes for enantioselective hydrogenation of olefins and other chiral transformations.