MRI: Acquisition of a Core Automated DNA Sequencing Facility

MRI：购置核心自动 DNA 测序设备

• 批准号: 0116165
• 负责人: Peter Straub
• 金额: $ 10.22万
• 依托单位: Stockton University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2004-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0116165&HistoricalAwards=false
• 关键词: MRI; Acquisition; Core; Automated; DNA

Abstract. NSF 0116165Acquisition of a Core Automated DNA Sequencing FacilityA grant has been awarded to Dr. Peter F. Straub, Dr. Brian J. Rogerson and Dr. Karen P. York of the Richard Stockton College of New Jersey to setup a DNA Sequencing Facility. The new Core Genetic Analysis Facility, once established, will enable automated DNA sequencing, DNA fragment analysis and integrated computer analysis of genetic data. This facility will be used to support student undergraduate research, faculty research and to enhance teaching in the Molecular and Genetic Biosciences at Stockton College.The main instrument acquired by the grant is an automated DNA Sequencer. Other instruments useful in running the sequencing reactions, specialized software packages, and supplies have been funded to add more research capabilities to the facility. To involve large numbers of students and faculty, two collaborative demonstration projects will be supported during the first three years of the grant. The first project will use sequencing and DNA fragment analysis to fingerprint and identify bacteria in subsurface aquifers. The results will provide information helpful to the study of large-scale geothermal energy use (such as at Stockton College). The second project will generate short DNA sequences from libraries of winter flounder genes in support of fisheries research. Both of these projects invite multi-user large-scale collaboration among students and faculty and will produce knowledge that is immediately useful to the scientific community. This project has the potential to transform the way that teaching and research are performed at a primarily undergraduate college like Richard Stockton College of NJ. The grant supports a facility that focuses on collaborative student-faculty research in Genetics. These opportunities are important for training undergraduate research students since Medicine, Pharmaceuticals and Biotechnology have been among the most important sectors of the economy whose growth has been directly influence by the revolutionary advancement in biological technologies (like DNA sequencing) over the past twenty years.

抽象的。NSF 0116165获得核心自动DNA测序设施新泽西州理查德·斯托克顿学院的Peter F.Straub博士、Brian J.Rogerson博士和Karen P.York博士获得了一笔赠款，用于建立DNA测序设施。新的核心遗传分析设施一旦建立，将使DNA自动测序、DNA片段分析和遗传数据的综合计算机分析成为可能。这一设施将用于支持斯托克顿学院的学生本科生研究、教师研究以及加强分子和遗传生物科学的教学。用于运行测序反应的其他有用仪器、专门的软件包和用品已经得到资助，以增加该设施的研究能力。为了吸引大量的学生和教职员工参与，两个合作示范项目将在拨款的头三年得到支持。第一个项目将使用测序和DNA片段分析来识别地下含水层中的细菌。研究结果将为地热能源的大规模利用(如斯托克顿学院)的研究提供有益的信息。第二个项目将从冬季比目鱼基因库中产生短DNA序列，以支持渔业研究。这两个项目都吸引了学生和教职员工之间的多用户大规模合作，并将产生立即对科学界有用的知识。这个项目有可能改变像新泽西州理查德·斯托克顿学院这样以本科为主的学院进行教学和研究的方式。这笔拨款支持一个专注于遗传学中师生合作研究的设施。这些机会对于培养本科生来说很重要，因为医药和生物技术一直是经济中最重要的部门，其增长直接受到过去20年来生物技术(如DNA测序)革命性进步的影响。