MRI: Acquisition of a MALDI/FT-ICR mass spectrometer for multidisciplinary research

MRI：购买 MALDI/FT-ICR 质谱仪用于多学科研究

• 批准号: 0116416
• 负责人: Elizabeth Stemmler
• 金额: $ 28.05万
• 依托单位: Bowdoin College
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0116416&HistoricalAwards=false
• 关键词: MRI; Acquisition; MALDI; FT; ICR

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Bowdoin College will acquire a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer equipped with external matrix-assisted laser desorption/ionization (MALDI) and electron ionization (EI) sources. Faculty at Bowdoin College, Bates College and the University of Southern Maine will have access to this equipment, which will enhance research in a number of areas including a) studies of gas-phase ion-molecule reactions; b) identification of biological, polymeric, and organometallic synthetic targets; and c) characterization of samples that include neurons from marine invertebrates, plant pigment extracts, soil samples, and oil residues from archaeological collections. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. This instrument will serve as a vehicle to educate students and faculty about the new technologies of MALDI and FT-ICR mass spectrometry. In addition, because this instrumental technique is well suited for the analysis of a wide range of samples, the FT-ICR will catalyze new approaches to research and new research activities in disciplines such as neuroscience, ecology, biology, environmental studies and archaeology.

从主要研究仪器（MRI）计划的这一奖项，化学系在鲍登学院将获得傅里叶变换离子回旋共振（FT-ICR）质谱仪配备外部基质辅助激光解吸/电离（MALDI）和电子电离（EI）源。 鲍登学院、贝茨学院和南缅因州大学的教师将可以使用这种设备，这将加强若干领域的研究，包括a）气相离子分子反应的研究; B）生物、聚合物和有机金属合成目标的鉴定;和c）表征样品，所述样品包括来自海洋无脊椎动物的神经元、植物色素提取物、土壤样品和来自考古学收藏品的油残留物。 质谱（MS）是一种用于探测紧密结构细节并获得大量有机、生物有机和有机金属分子的分子组成的技术。该仪器将作为一种工具，教育学生和教师有关MALDI和FT-ICR质谱的新技术。 此外，由于这种仪器技术非常适合分析各种样品，FT-ICR将促进神经科学，生态学，生物学，环境研究和考古学等学科的新研究方法和新研究活动。