Deep Arthropod Phylogeny from 100 Targeted Nuclear Coding-region Sequences

100 个目标核编码区序列的深层节肢动物系统发育

• 批准号: 0120635
• 负责人: Clifford Cunningham
• 金额: $ 134.49万
• 依托单位: Duke University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-10-01 至 2007-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0120635&HistoricalAwards=false
• 关键词: Deep; Arthropod; Phylogeny; 100; Targeted

DEB-0120635Clifford Cunningham, Joel Martin, Jermoe Regier, Jeffrey Schultz & Jeffrey ThorneA grant has been awarded to an interdisciplinary team of researchers from Duke University, University of Maryland, University of Maryland Biotechnology Institute, North Carolina State University, and the Natural History Museum of Los Angeles County. This grant will support the largest effort to date to solve the major questions in the evolution of the arthropods. The arthropods -- which include insects, shrimp, centipedes, horshoe crabs, spiders and ticks -- represent more species than the rest of the animals combined. Despite more than a decade of molecular work, the relationships of these major groups of arthropods are not known. This grant will use information from the three completely sequenced animal genomes (human, worm, and fly) to help us obtain a giant dataset of nuclear protein coding sequences from 85 representative arthropod species. This dataset will include approximately 50,000 base pairs of DNA sequences per species, which is more than 10 times larger than the largest existing dataset.This project will not only decide the relationships of the major groups of arthropods, but will tell us which group of marine crustaceans (shrimps , lobsters and crabs) are the closest relatives to the insects, which represent the most successful invasion of land by any animal group. This grant will also support development of new statistical methods to estimate the dates of the major events in arthropod evolution, and, includes an innovative plan to develop teaching modules to expose underprivileged K-12 students in the Los Angeles region, and elsewhere in the country, to the evolution of the charismatic Arthropoda.

clifford Cunningham, Joel Martin, Jermoe Regier， Jeffrey Schultz & & Jeffrey thora获得了一项资助，该资助由来自杜克大学、马里兰大学、马里兰大学生物技术研究所、北卡罗莱纳州立大学和洛杉矶县自然历史博物馆的跨学科研究人员组成。这笔拨款将支持迄今为止解决节肢动物进化中的主要问题的最大努力。节肢动物——包括昆虫、虾、蜈蚣、马蹄蟹、蜘蛛和蜱虫——代表的物种比其他动物的总和还要多。尽管经过了十多年的分子研究，这些主要节肢动物群体之间的关系仍不为人所知。该基金将使用来自三种完全测序的动物基因组（人类，蠕虫和苍蝇）的信息来帮助我们获得85种代表性节肢动物物种的核蛋白编码序列的庞大数据集。该数据集将包括每个物种约50,000个碱基对的DNA序列，比现有最大的数据集大10倍以上。这个项目不仅将决定节肢动物主要类群的关系，而且将告诉我们哪一类海洋甲壳类动物（虾、龙虾和螃蟹）是昆虫的近亲，昆虫代表了任何动物群体中最成功的入侵陆地。这笔拨款还将支持开发新的统计方法，以估计节肢动物进化主要事件的日期，并包括一项创新计划，以开发教学模块，使洛杉矶地区和全国其他地方贫困的K-12学生了解有魅力的节肢动物的进化。