CAREER: Globular Macromolecules with Functionalized Interiors

化学系的先进材料计划将这一奖项授予杜兰大学。获得这一职业奖后，Sankaran Thayumanavan教授将研究大分子中的分子相互作用，并将设计功能和动态树枝状大分子的参数。同时具有疏水和亲水基团的树枝状大分子将被设计、合成和功能化，以提供在极性溶剂中的亲水外表面和在非极性溶剂中的亲水外表面。这些研究将为开发具有功能效用的大分子的设计二级结构提供关键概念。有了这些树状大分子，就有可能在极性介质中将非极性有机底物隔离到这些树状大分子的内部，用于催化、相转移反应、药物输送系统和传感器。拟议的教育外展计划杜兰科学学者计划是一个强大的教育计划，该计划将使当地高中生接触到科学和工程计划。PI是该项目的联合主任，在其他教职员工的帮助下，将在秋季和春季学期为高三和高三学生提供化学、物理、细胞生物学、分子生物学、环境科学、化学工程、机械工程和生物医学工程方面的课程。具有官能团的新型树枝状聚合物可用于极性和非极性溶剂中，在催化、相转移反应、药物输送系统和传感器等方面有应用。拟议的杜兰科学学者计划将使高中生接触到科学和工程学科的不同方面，并将为他们在大学水平的科学和工程项目中进修做好准备。

The Advanced Materials Program in the Division of Chemistry makes this award to Tulane University. With this Career award, Professor Sankaran Thayumanavan will study molecular interactions in macromolecules, and will design parameters for functional and dynamic dendrimers. Dendrimers with both hydrophobic and hydrophilic groups will be designed, synthesized and functionalized to provide hydrophilic outer surfaces in polar solvents and hydrophilic outer surfaces in apolar solvents. The studies will provide key concepts for the development of designed second order structure in macromolecules with functional utility. With these dendrimers, it would be possible to sequester apolar organic substrates into these dendrimeric interiors in polar media for applications in catalysis, phase transfer reactions, drug delivery systems and sensors. The proposed educational outreach program 'Tulane Science Scholars Program is a strong educational program, and this program will expose local high school students to science and engineering programs. The PI, the Co-director of the program with the help of other faculty members, will be provide courses to high school juniors and seniors in Chemistry, Physics, Cell Biology, Molecular Biology, Environmental Sciences, Chemical Engineering, Mechanical Engineering and Biomedical Engineering during Fall and Spring semesters. New dendrimeric polymers with functional groups may be used in polar and apolar solvents with applications in catalysis, phase transfer reactions, drug delivery systems and sensors. The proposed Tulane Science Scholars Program will expose high school students in different aspects of science and engineering subjects, and will prepare them for advanced studies in science and engineering programs at college level.