CAREER: Globular Macromolecules with Functionalized Interiors

化学系的先进材料计划将此奖项授予杜兰大学。 有了这个职业奖，Sankaran Thayumanavan教授将研究大分子中的分子相互作用，并将设计功能和动态树枝状聚合物的参数。 具有疏水和亲水基团的树枝状聚合物将被设计、合成和官能化以提供在极性溶剂中的亲水外表面和在非极性溶剂中的亲水外表面。这些研究将为开发具有功能实用性的高分子二级结构设计提供关键概念。 使用这些树枝状聚合物，将有可能在极性介质中将非极性有机底物螯合到这些树枝状聚合物内部，用于催化、相转移反应、药物递送系统和传感器中的应用。 拟议中的教育推广计划“杜兰科学学者计划”是一个强大的教育计划，该计划将使当地高中学生接触科学和工程项目。 PI，该计划的联合主任与其他教师的帮助下，将提供课程，高中三年级和四年级学生在化学，物理，细胞生物学，分子生物学，环境科学，化学工程，机械工程和生物医学工程在秋季和春季学期。具有官能团的新型树枝状聚合物可用于极性和非极性溶剂中，并可应用于催化、相转移反应、药物递送系统和传感器。 拟议中的杜兰科学学者计划将使高中生接触科学和工程学科的不同方面，并为他们在大学阶段的科学和工程课程的高级学习做好准备。

The Advanced Materials Program in the Division of Chemistry makes this award to Tulane University. With this Career award, Professor Sankaran Thayumanavan will study molecular interactions in macromolecules, and will design parameters for functional and dynamic dendrimers. Dendrimers with both hydrophobic and hydrophilic groups will be designed, synthesized and functionalized to provide hydrophilic outer surfaces in polar solvents and hydrophilic outer surfaces in apolar solvents. The studies will provide key concepts for the development of designed second order structure in macromolecules with functional utility. With these dendrimers, it would be possible to sequester apolar organic substrates into these dendrimeric interiors in polar media for applications in catalysis, phase transfer reactions, drug delivery systems and sensors. The proposed educational outreach program 'Tulane Science Scholars Program is a strong educational program, and this program will expose local high school students to science and engineering programs. The PI, the Co-director of the program with the help of other faculty members, will be provide courses to high school juniors and seniors in Chemistry, Physics, Cell Biology, Molecular Biology, Environmental Sciences, Chemical Engineering, Mechanical Engineering and Biomedical Engineering during Fall and Spring semesters. New dendrimeric polymers with functional groups may be used in polar and apolar solvents with applications in catalysis, phase transfer reactions, drug delivery systems and sensors. The proposed Tulane Science Scholars Program will expose high school students in different aspects of science and engineering subjects, and will prepare them for advanced studies in science and engineering programs at college level.