2002 Tetrapyrroles Gordon Conference; July 14 -19, 2002, Newport, Rhode Island

2002年四吡咯戈登会议；

• 批准号: 0200930
• 负责人: Gloria Ferreira
• 金额: $ 0.5万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0200930&HistoricalAwards=false
• 关键词: 2002; Tetrapyrroles; Gordon; Conference; July

This application requests support for the 19 th Gordon Research Conference on theChemistry and Biology of Tetrapyrroles, to be held at Salve Regina University,Newport, RI, from July 14-19, 2002. The specific aims of this conference are thefollowing:1) To provide a forum for discussion of recent unpublished data by scientists withcommon interest in the study of the chemistry and biology of tetrapyrrole compounds.2) To promote the exchange of ideas between established and new investigators from awide variety of scientific disciplines (e.g., chemists, biochemists, clinicians, plantbiologists, microbiologists, biotechnologists) by providing ample discussion timefollowing formal presentations, by holding poster sessions which serve as a focus forthe discussion of common interests.This biennial interdisciplinary conference has stimulated collaborations between basicbiologists, chemists and clinicians interested in tetrapyrroles for more than threedecades. In association with proteins, tetrapyrroles serve diverse roles as biologicalredox catalysts, in the harvesting of light energy, in the activation and delivery ofoxygen, and as signaling molecules. Free tetrapyrroles are also essential nutrients(e.g., vitamin B12), serve as regulators of gene expression (e.g., hemes), and are beingutilized as therapeutic agents (e.g., photodynamic cancer therapy, target delivery ofradionuclides). Owing to their photodynamic activity, toxicity and lipophilicity, theaccumulation of tetrapyrroles (e.g., porphyrins, bilirubin) is associated with numerouspathologies of the skin, liver and brain. For these reasons, this conference representsan important venue for exchange between basic and applied researchers ontetrapyrroles and for refinement of new tools and therapies for development by thebiomedical industry. Funds requested in this application are targeted to support 10young investigators who have not previously had the opportunity to attend thisconference and for travel of two young ioprimarily undergraduate institutionleresearchers. The sessions, which highlight recent technological progress, will include22 invited speakers, a plenary lecturer and 14 discussion leaders. All of theseindividuals have been selected for their scientific excellence, recent innovative workand contribution to the breadth of the program. The remaining 100 conferees will bechosen to ensure a broad representation of women, ethnicity and young scientists fromvarious disciplines in academia, medical research institutions and industry. Strengthsof this ongoing Gordon conference are its high disciplinary diversity, integration ofresearch from basic chemistry through practical and clinical applications, focus onnew unpublished work, time for discussion, informal atmosphere, and ban ondissemination of conference proceedings, (which it is essential to assureconfidentiality when discussing unpublished results).

本申请请求对将于2002年7月14-19日在Salve Regina大学，纽波特，RI举行的第19届四吡咯化学和生物学戈登研究会议的支持。本次会议的具体目标如下：1）为对四吡咯化合物的化学和生物学研究有共同兴趣的科学家提供一个讨论最新未发表数据的论坛。2）促进来自各种科学学科（例如，化学家，生物化学家，临床医生，植物生物学家，微生物学家，生物技术学家）通过提供充分的讨论时间后，正式介绍，通过举办海报会议，作为一个焦点为共同利益的讨论。这个两年一度的跨学科会议已刺激之间的合作basicbiologists，化学家和临床医生感兴趣的tetrapyrroles超过threedecades。与蛋白质结合，四吡咯作为生物氧化还原催化剂，在光能的收集，氧的活化和传递以及作为信号分子中起着不同的作用。游离四吡咯也是必需营养素（例如，维生素B12），作为基因表达的调节剂（例如，血红素），并被用作治疗剂（例如，光动力癌症治疗、放射性核素的靶向递送）。由于它们的光动力活性、毒性和亲脂性，四吡咯（例如，卟啉、胆红素）与皮肤、肝脏和大脑的数字病理学有关。由于这些原因，本次会议代表了一个重要的场所，为基础和应用研究人员之间的交流tetrapyrroles和完善的新工具和疗法的发展，由thebiomedical行业。本申请中要求的资金旨在支持10名以前没有机会参加本次会议的年轻研究人员，以及两名年轻的印度大学本科研究人员的旅行。这些会议强调了最近的技术进步，将包括22名特邀演讲者，一名全体演讲者和14名讨论领导人。所有这些人都是因为他们的科学成就，最近的创新工作和对该计划广度的贡献而被选中的。剩下的100名与会者将被挑选出来，以确保来自学术界、医学研究机构和工业界各个学科的妇女、种族和年轻科学家的广泛代表性。这个正在进行的戈登会议的优势是它的高度学科多样性，从基础化学到实际和临床应用的研究整合，关注新的未发表的工作，讨论时间，非正式的气氛，以及禁止传播会议记录（在讨论未发表的结果时，确保保密性至关重要）。