NER: Torque Spectroscopy for Nanosystem Characterization and Fabrication

NER：用于纳米系统表征和制造的扭矩光谱

• 批准号: 0210210
• 负责人: Daniel Cole
• 金额: $ 10万
• 依托单位: Duke University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-15 至 2004-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0210210&HistoricalAwards=false
• 关键词: NER; Torque; Spectroscopy; Nanosystem; Characterization

This project was received in response to Nanoscale Science and Engineering initiative, NSF 01-157, category NER. The purpose of this research is to develop the technology to deliver regulated torques to nanosystems; such torques would be on the order of piconewton-nanometers. Helicallv structured light possessing angular momentum will be used in an optical trapping arrangement to deliver angular momentum to trapped particles thereby applying a torque to the trapped object. Position and orientation of a trapped object will be achieved with a trapping beam constructed from the interference of a helical wave front and a plane wave. This research focuses on developing an optical trap using a conventional single-beam trap architecture; constructing the requisite helically-structured laser beam modes as Laguerre-Gaussian (LG) beam modes and constructing an interference pattern between LG beam modes and plane-wave beam modes. Torque spectroscopy experiments of biomolecules will be performed. Candidate molecules are coiled-coil proteins like myosin, modular matrix proteins like fibronectin and tenascin, and the DNA double helix.This research program will have a broad impact in the advancement of knowledge, education, industry and technology. An optical torque-trap is an enabling technology for the comprehensive development of nanoscience and engineering, and will have wide application in nanotechnology from characterization to fabrication. In nanoscale biosystems it would be used to provide an understanding of the behavior of single molecules. For nanoscale structures, it would enable the characterization of novel nanoscale structures and phenomena which depend upon rotary motion . Finally for nanoscale manufacturing processes it would enable new nanofabrication processes which would depend upon the manipulation of particles in six-dimensions Other applications include measuring the torque and power output of rotary nanomotors, measuring the bending strength of molecules, measuring the drag on nanobearings, and driving nanosystems by photonic components. This program will also have impacts in new curriculum for graduate students, combining elements of engineering and physics for nanoscience and engineering; the study of nanosystems and nanobiosystems; training opportunities for undergraduate students in nanotechnology through participation in research projects; and industrial collaboration providing technology transfer and training opportunities for faculty, research associates, and students.

该项目是在响应纳米科学和工程倡议，NSF 01-157，类别NER。 这项研究的目的是开发技术，以提供调节扭矩的纳米系统，这样的扭矩将在皮牛顿纳米的顺序。 具有角动量的螺旋结构光将用于光学捕获装置中，以将角动量传递到被捕获的粒子，从而向被捕获的物体施加扭矩。利用平面波和螺旋波干涉形成的俘获光束，可以实现被俘获物体的定位和定向。本研究的重点是开发一个光学陷阱使用传统的单光束陷阱架构，构建必要的螺旋结构的激光束模式的拉盖尔-高斯（LG）光束模式和LG光束模式和平面波光束模式之间的干涉图案。将进行生物分子的扭矩光谱实验。候选分子是卷曲螺旋蛋白如肌球蛋白，模块化基质蛋白如纤维连接蛋白和腱生蛋白，以及DNA双螺旋。这项研究计划将在知识，教育，工业和技术的进步产生广泛的影响。光学转矩阱是纳米科学与工程综合发展的一项重要技术，在纳米技术从表征到加工的各个环节都有着广泛的应用前景。在纳米生物系统中，它将被用来提供对单个分子行为的理解。对于纳米级结构，它将能够表征依赖于旋转运动的新型纳米级结构和现象。最后，对于纳米级制造工艺，它将使新的纳米制造工艺成为可能，这将取决于在六维空间中对粒子的操纵。其他应用包括测量旋转纳米马达的扭矩和功率输出，测量分子的弯曲强度，测量纳米轴承上的阻力，以及通过光子组件驱动纳米系统。 该计划也将对研究生的新课程产生影响，结合纳米科学和工程的工程和物理元素;纳米系统和纳米生物系统的研究;通过参与研究项目为本科生提供纳米技术培训机会;以及为教师，研究人员和学生提供技术转让和培训机会的工业合作。