Organosulfur Natural Products Chemistry

该项目将探索天然来源的不寻常的有机硫化合物的化学。 首先，将从非洲、南美洲和中东的葱属植物中分离、鉴定和表征新的有机硫化合物。 然后将研究这些新的有机硫化合物的合成和有机反应化学。 天然产物的热分解也将被研究，因为这项研究将与烹饪后植物成分的命运有关。有了这个少数民族研究规划奖，有机和大分子化学计划支持博士的研究。位于奥尔巴尼的纽约州立大学化学系的穆萨说。 Musah博士将致力于从非洲、南美洲和中东的葱属植物中分离、鉴定和表征新的有机硫化合物。 本文将对这些新的含硫有机化合物的合成和有机反应化学进行研究。 还将研究天然产品的热分解，因为这项研究将与烹饪后植物成分的命运有关。 已知葱属中的其他植物含有具有许多生物医学应用的化合物，因此作为这项工作的结果，很有可能发现具有生物活性的新化合物。 在这项工作的过程中接受培训的学生将获得特殊化学品和制药行业所需的技能。

This project will explore the chemistry of unusual organosulfur compounds of natural origin. Initially, new organosulfur compounds from a variety of plants in the allium (garlic and onion) genus from Africa, South America and the Middle East will be isolated, identified and characterized. Synthesis and study of the organic reaction chemistry of these new organosulfur compounds will then be investigated. Thermal decomposition of the natural products will also be studied since this study will be relevant to the fate of the plant constituents upon cooking.With this Minority Research Planning Grant award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Rabi A. Musah of the Department of Chemistry at the State University of New York at Albany. Dr. Musah will work on the isolation, identification, and characterization of new organosulfur compounds from a variety of plants in the allium (garlic and onion) genus from Africa, South America and the Middle East. The synthesis and study of the organic reaction chemistry of these new organosulfur compounds will then be investigated. Thermal decomposition of the natural products will also be studied since this study will be relevant to the fate of the plant constituents upon cooking. Other plants within the allium genus are known to contain compounds with a host of biomedical science applications so there is a high probability that new compounds with biological activities will be discovered as a result of this work. Students trained during the course of this work will gain skills needed by the speciality chemicals and pharmaceutical industries.