MRI: Acquisition of a 500 MHz NMR Spectrometer for Research and Training

该奖项由重大研究仪器计划(MRI)和化学研究仪器计划(CRIF)支持。有了它，纽约州立大学奥尔巴尼分校的Rabi Musah教授和他的同事们获得了一台500 MHz的核磁共振(核磁共振)光谱仪。核磁共振光谱仪测量样品中原子核在光刺激下发出的微弱信号。这些信号能够识别所研究的化学物质或材料中的原子(例如，氢、碳和其他元素)。核磁共振是一种强大的分析技术，用于表征需要鉴定的反应产物、蛋白质和其他生物物种或未知物质。因此，核磁共振波谱仪对于化学、生物和环境研究是必不可少的。该仪器是用来培训学生的技术，为他们的职业生涯做准备。光谱仪是大奥尔巴尼地区其他机构可用的资源，包括圣罗斯学院和斯基德莫尔学院。核磁共振光谱仪的获奖旨在加强各级的研究和教育。该仪器可能会影响合成和表征有机硫和有机硒化合物，以及有机硫天然产物，如植物化学防御分子的研究。该仪器用于研究用于制备能源相关材料的异金属分子前驱体。利用该仪器的数据，对富碳皮碗、纳米带和翘曲纳米薄膜的研究取得了进展。光谱仪是探索生物活性物种合成的几个项目中不可或缺的工具。这些包括合成小分子多肽天然产物的方法，以及多肽、蛋白质和糖蛋白的化学合成。还在研究天然修饰的RNA核苷、核苷酸和寡核苷酸的合成及其晶体结构的测定。

This award is supported by the Major Research Instrumentation Program (MRI) and the Chemistry Research Instrumentation Program (CRIF). With it, Professor Rabi Musah from SUNY Albany and colleagues acquired a 500 MHz nuclear magnetic resonance (NMR) spectrometer. A NMR spectrometer measures weak signals from atomic nuclei in a sample when stimulated by light. These signals enable identification of the atoms (for example, hydrogen, carbon, and other elements) in the chemical or material under study. NMR is a powerful analytical technique used to characterize reaction products, proteins and other biological species, or unknown substances which need to be identified. Consequently, NMR spectrometers are essential to chemistry, biological and environmental research. The instrument is used to train students in the technique preparing them for their careers. The spectrometer is a resource available to other institutions in the greater Albany region including the College of St. Rose and Skidmore College. The award of the NMR spectrometer is aimed at enhancing research and education at all levels. This instrument may impact studies synthesizing and characterizing organosulfur and organoselenium compounds, and organosulfur natural products such as plant chemical defense molecules. The instrument is used for investigating heterometallic molecular precursors for the preparation of energy-related materials. Research on carbon-rich pi-bowls, nanobelts and warped nanographene sheets advance with data from the instrument. The spectrometer is an integral tool in several projects exploring the syntheses of biologically active species. These include synthetic approaches to small-molecule peptide natural products, and the chemical synthesis of peptides, proteins and glycoproteins. Also under investigation are the synthesis of naturally modified RNA nucleosides, nucleotides and oligonucleotides and the determination of their crystal structures.