Characterisation of Arabidopsis ABA receptors

高等植物是固着的生物体，它们进化出了适应环境挑战的高度可塑性。病原体和非生物胁迫如干旱和盐胁迫严重影响植物的性能和生产力。植物激素脱落酸（阿坝）是植物对生物和非生物胁迫响应的内源信使。此外，阿坝是在非胁迫条件下微调生长和发育所必需的。最近的识别阿坝受体和新兴的组合组装的众多不同的阿坝受体提供了激励，提出详细的分析阿坝受体复合物和它们与已知的靶蛋白的相互作用。此外，阐明了阿坝受体活性调节的分子机制以及ABA-受体复合物的三维结构分析。

Higher plants are sessile organisms that have evolved a high plasticity for adaptation to environmental challenges. Pathogens and abiotic stress such as drought and salt stress severely impact plant performance and productivity. The phytohormone abscisic acid (ABA) serves as an endogenous messenger in biotic and abiotic stress responses. In addition, ABA is required to fine-tune growth and development under non-stress conditions. The recent identification of ABA receptors and the emerging combinatorial assembly of a multitude of different ABA receptors provide the incentive to propose the detailed analysis of ABA receptor complexes and their interaction with known target proteins. In addition, the elucidation of the molecular mechanism regulating ABA receptor activity as well as the three-dimensional structural analysis of an ABA-receptor complex is proposed.