CAREER: Biomolecule-Macromolecule Interactions at Surfaces and Interfaces

弗吉尼亚理工学院的Alan Esker教授得到了分析和表面化学项目的支持，研究磁性纳米颗粒及其在仿生脂质系统中的聚集、吸附、运输和粘弹性。 施加的磁场可以改变基本的脂质-纳米颗粒相互作用，这与药物递送和治疗应用特别相关。 该CAREER奖项也支持PI的目标，即通过本科生的创新研究经验吸引学生进入大分子物理化学，并将酶动力学研究作为物理化学课程的一部分。磁性纳米颗粒在分离、生物传感、治疗剂和磁共振成像造影剂的靶向递送方面引起了相当大的关注。 对它们与膜相互作用的基础研究将最终导致这些应用的改进。

Professor Alan Esker of Virginia Polytechnic Institute is supported by the Analytical and Surface Chemistry Program to study magnetic nanoparticles and their aggregation, adsorption, transport and viscoelastic properties in biomimetic lipid systems. Applied magnetic fields can alter fundamental lipid-nanoparticle interactions, which are particularly relevant for drug delivery and therapeutic applications. This CAREER award also supports the PI's goal of attracting students to macromolecular physical chemistry with innovative research experiences for undergraduates and research on enzyme kinetics as part of the physical chemistry course.Magnetic nanoparticles have attracted considerable attention for separations, biosensing, targeted delivery of therapeutic agents and magnetic resonance imaging contrast agents. Basic research into their interactions with membranes will ultimately lead to improvements in these applications.