Reactivity and Synthesis of Fluoroorganic Compounds and Reactive Intermediates

本研究的重点是研究五氟化硫自由基和三氟甲烷阴离子(Ruppert试剂)在制备氟化有机化合物中的反应活性。这项研究涉及详细的反应机理的阐述，通过使用热力学和动力学来研究区域化学和立体化学问题，因为它们适用于反应中间体中的结构-活性关系。通过这一持续的奖项，有机化学和高分子化学项目正在支持小威廉·R·多尔比尔博士的研究和教育努力。他是佛罗里达大学化学系的。多尔比尔教授将把他的工作重点放在构建商业上可行的方法上，以准备用于半导体行业的材料。将开发安全、经济和环境友好的有机氟化合物生产方法。该奖项的教育活动将包括对佛罗里达大学的研究生、博士后助理、访问学者和本科生的培训。

The focus of this research is to study the reactivity of sulfurpentafluoride radicals and trifluoromethane anions (Ruppert's reagent) for the preparation of fluoronated organic compounds. This study involves the elaboration of detailed reaction mechanisms by the use of thermodynamics and kinetics to examine regiochemical and stereochemical issues as they apply to structure-activity relationships in the reaction intermediates. With this continuing award, the Organic and Macromolecular Chemistry Program is supporting the research and educational efforts of Dr. William R. Dolbier, Jr. of the Department of Chemistry at the University of Florida. Professor Dolbier will focus his work on the construction of commercially feasible methods for the preparation of materials for use in the semiconductor industry. Methods for safe, economical and environmentally friendly methods for the production of organofluorine compounds will be developed. The educational activities of the award will include the training of graduate students, post-doctoral associates, visiting scholars and undergraduates at the University of Florida.