Digital Interference Holography: Development of a New Tomographic Microscopy Instrument

南佛罗里达大学的Myung Kim博士获得了一笔赠款，用于进一步开发一种用于显微光学切片和断层成像的新型仪器。该仪器基于最近引进的波长扫描数字干涉全息术(DIH)原理。拟议的三年研究计划旨在：(1)开发关键参数与实际显微成像应用相一致的原型仪器；(2)建立图像库，以便将成像方法和仪器应用于广泛的标本；以及(3)开发相关的生物医学应用和新技术。其中一个重要的长期目标是开发一种紧凑、通用和经济的成像系统，这将有助于进一步扩大应用范围。随着数字干涉全息术能力的充分发展，它提供了一种简单而通用的方式来获取和处理微观物体的三维数字模型，从而有可能对光学显微镜和层析成像的一般领域产生影响。

A grant has been awarded to Dr. Myung Kim at the University of South Florida to further develop a novel instrument for microscopic optical sectioning and tomographic imaging. The instrument is based on the recently introduced principle of wavelength scanning digital interference holography (DIH). The proposed three-year research program aims to: (1) develop a prototype instrument with key parameters consistent with practical microscopic imaging applications; (2) build up an image gallery for the purpose of applying the imaging methods and the instrument to a wide range of specimens; and (3) develop relevant biomedical applications and new techniques. One of the important long-term goals is to develop a compact, versatile, and economical imaging system, which will help further widen the range of applications. With full development of its capabilities, digital interference holography has the potential to impact the general field of optical microscopy and tomography by providing a simple and versatile mode of acquiring and manipulating three-dimensional digital model of microscopic objects.