RUI: Acquisition of DNA Microarray Technology for Biological Research

RUI：收购 DNA 微阵列技术用于生物研究

• 批准号: 0301634
• 负责人: Craig Vierra
• 金额: $ 6.67万
• 依托单位: University of the Pacific
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0301634&HistoricalAwards=false
• 关键词: RUI; Acquisition; DNA; Microarray; Technology

A grant has been awarded to the University of the Pacific (UOP) under the direction of Dr. Craig Vierra for the acquisition of a DNA microarray spotter, and a microarray scanner with software for data collection and analysis. Projects that will utilize this instrumentation include studies of genes regulated by basic helix-loop-helix proteins; identification of genes involved in peroxisome biogenesis in the methylotrophic yeast Pichia pastoris; identification of protein factors involved in the Ah receptor signaling pathway; identification of novel silk genes in spiders; identification of genes involved in DNA repair in Drosophila melanogaster; and the involvement of transcription factors in Caenorhabditis elegans development. The acquisition of DNA microarray technology for biological research will provide state-of-the-art research technology at UOP and support a program dedicated to training undergraduates at the highest level. The acquisition of this equipment will substantially impact faculty research for many members located in the Biology and Chemistry Departments and School of Pharmacy, as well as provide invaluable training and experience for science graduate students and undergraduates at UOP and California State University, Stanislaus. The equipment will help create a pedagogical environment to enhance learning for undergraduates seeking advanced science degrees and vocations in biotechnology.

在克雷格·维埃拉博士的指导下，向太平洋大学提供了一笔赠款，用于购置一台DNA微阵列探测仪和一台装有数据收集和分析软件的微阵列扫描仪。将利用这种仪器的项目包括：受碱性螺旋-环-螺旋蛋白调控的基因的研究；在甲醇营养酵母巴斯德毕赤酵母中参与过氧化酶体生物发生的基因的鉴定；涉及ah受体信号通路的蛋白质因子的鉴定；蜘蛛中新的丝蛋白基因的鉴定；果蝇DNA修复相关基因的鉴定；以及转录因子在秀丽线虫发育中的参与。收购用于生物研究的DNA微阵列技术将为UOP提供最先进的研究技术，并支持一个致力于培养最高水平本科生的计划。购买这种设备将对位于生物、化学系和药学院的许多成员的教职研究产生重大影响，并为UOP和加州州立大学斯坦尼斯劳斯分校的理科研究生和本科生提供宝贵的培训和经验。这些设备将有助于创造一个教学环境，促进寻求高等科学学位和生物技术职业的本科生的学习。