Microarray Workshops for Undergraduate Faculty and Students: Rocket Science or Basic Science? To be held in Seattle, WA, Summer of 2003.

面向本科生的微阵列研讨会：火箭科学还是基础科学？波莫纳学院（Pomona College）的劳拉·胡普斯（Laura Hoopes）博士获得了一笔赠款，将于2003年夏季举办一次关于微阵列在本科教学和研究项目中的应用的教师研讨会。今年夏天，在系统生物学研究所的研讨会上，来自不同机构（小型和大型私人机构，小型和大型公共机构，主要是代表性不足的机构）的11名教师将讨论问题，测试方法，并为2004年开放研讨会的提案制定计划，主题是在本科生的教学/学习中应用这种最先进的全球基因表达分析方法。参加2003年研讨会的教师包括该项目的PI和copi，伯明翰阿拉巴马大学NSF微阵列推广项目的PI， GCAT湿实验室程序的用户，微阵列软件和统计分析方面的专家，以及课程专家。参与者将包括来自大大小小的公立和私立机构的教员，其中包括至少一所主要为科学领域代表性不足的学生服务的机构。讲习班成员将讨论第二个夏季的计划，届时将在TIGR的支持下在乔治敦大学举办一次公开讲习班，并开始为该讲习班编写提案。需要特别注意的问题将包括本科生和第二次研讨会中使用这些方法的受众范围，采用我们的方法的财务方面，成功整合这种方法所需的课程变化的水平和强度，以及湿实验室和数据分析中最佳使用的后勤和方法。此外，研讨会将测试三种不同的方法在实际微阵列上标记酵母的总RNA，并评估这些方法的优缺点，以供学生使用。本次研讨会最重要的成果将是向美国国家科学基金会提出一项新的建议，以支持一个与本科生一起使用干湿微阵列实验室的开放研讨会，以满足我们在国家会议上遇到的这样一个事件的需求，当时我们展示了主动教学基因组联盟在课程和学生研究中使用微阵列的结果。第二个成果将是对本科生使用微阵列的范围、财务和课程/逻辑影响的讨论，该讨论将放在GCAT网站上供公众访问，并由GCAT成员在美国微生物学会和美国细胞生物学学会的全国会议上以及ASCB的在线教育期刊上发表。第三个输出将是一套针对三种不同标记方法和测试的干实验室软件/数据集的修订方案，以及讲习班参与者对其优缺点的评论，用于GCAT网站和开放讲习班实验室手册。第四个成果将是准备10名教员（第11人是外部顾问，所以我们不指望他参加我们的公开研讨会）领导2004年的研讨会，并准备领导未来的研讨会。

Microarray workshop for undergraduate faculty: Rocket science or basic science? A grant has been awarded to Dr. Laura Hoopes at Pomona College to conduct a faculty workshop in summer, 2003 on use of microarrays for undergraduate teaching and research projects. In the workshop at the Institute for Systems Biology this summer, 11 faculty from a variety of institutions (small and large private, small and large public, predominantly underrepresented) will discuss issues, test methods, and make plans for a proposal for an open workshop in 2004 on applications for this state of the art method in global gene expression analysis in teaching/learning for undergraduates. The faculty for the 2003 workshop include the PI and coPIs for this grant, the PI for a different NSF microarray outreach grant at Univ Alabama, Birmingham, users of the wet laboratory procedures from GCAT, experts in software and statistical analysis of microarrays, and a curriculum expert. The participants will include faculty from large and small public and private institutions, including at least one institution serving mainly students underrepresented in science. The workshop members will discuss the plans for a second summer in which an open workshop would be presented at Georgetown University with the support of TIGR, and begin the preparation of a proposal for that workshop. The issues for special attention will include the scope of the audience for usese of these methods with undergraduates and for the second workshop, the financial aspects of adopting our methods, the level and intensity of curricular change necessary to incorporate this methodology successfully, and the logistics and methods best used in the wet laboratory and the data analysis. In addition, the workshop will test three different approaches to labeling total RNA of yeast on actual microarrays, and evaluate the strengths and weaknesses of these approaches for use with students. The most important outcome of broader significance from this workshop will be a new proposal to NSF to support an open workshop on using wet and dry microarray laboratories with undergraduate students, to meet the demand for such an event that we encountered at national meetings when presenting the results of Genome Consortium for Active Teaching's uses of microarrays in courses and student research. The second output will be a discussion of the scope, financial, and curriculum/logistic implications of using microarrays with undergraduates to be placed on the GCAT web site for public access, and presented by GCAT members at national meetings of the American Society for Microbiology and the American Society for Cell Biology, as well as the online educational journal of the ASCB. The third output will be a revised set of protocols for the three different labeling methods and the tested dry laboratory software/data sets, with commentary from the workshop participants on their good and bad points, for the GCAT web site and the open workshop laboratory manual. The fourth outcome will be preparation of 10 faculty members (the 11th person is an outside advisor, so we would not expect him to participate in our open workshop) to lead the workshop proposed for 2004, and be prepared to lead future workshops.