Incorporation of Nuclear Magnetic Resonance Spectroscopy Throughout the Chemistry Curriculum

将核磁共振波谱学纳入整个化学课程

• 批准号: 0310728
• 负责人: Susan Ensel
• 金额: $ 5.24万
• 依托单位: Hood College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2005-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0310728&HistoricalAwards=false
• 关键词: Incorporation; Nuclear; Magnetic; Resonance; Spectroscopy

Chemistry (12) NMR methodologies are being incorporated into a discovery-based chemistry curriculum by using NMR experiments, developed at other sites, and adapted to enhance the education of a predominantly female population. The experiments being adapted come from various disciplines and have been published in the Journal of Chemical Education. However, the experiments also serve to enhance a larger picture of the curriculum. An Anasazi Instruments Fourier Transform 60 MHz NMR will be acquired to perform the experiments in the different laboratory courses in the curriculum. In the organic chemistry laboratory students are using the NMR to determine the structures of the products they synthesize. Students performing a large multi-step research synthesis project in the second semester organic course are using the NMR to provide clear evidence of the successful completion of the student-designed syntheses. In the analytical chemistry courses, students are exploring the quantitative capabilities of the NMR spectrometer and the influence of changing acquisition parameters on spectral quality. In the biochemistry courses, the NMR is being used to explore peptide conformation and the kinetics of glucose metabolism. The instrumentation obtained for this project is being used in conjunction with instrumentation purchased from previous NSF grants to the department.

化学（12）正在利用在其他地点开发的核磁共振实验，将核磁共振方法纳入以发现为基础的化学课程，并加以调整，以加强以女性为主的人口的教育。正在改编的实验来自不同的学科，并已发表在化学教育杂志上。 然而，这些实验也有助于提高课程的整体水平。 将获得Anasazi仪器傅立叶变换60 MHz NMR，以执行课程中不同实验室课程的实验。 在有机化学实验室里，学生们正在使用核磁共振来确定他们合成的产物的结构。在第二学期有机课程中进行大型多步骤研究合成项目的学生正在使用NMR来提供学生设计的合成成功完成的明确证据。在分析化学课程中，学生将探索NMR光谱仪的定量能力以及改变采集参数对光谱质量的影响。 在生物化学课程中，核磁共振被用来研究肽的构象和葡萄糖代谢的动力学。 为该项目获得的仪器正在与从以前的NSF赠款购买的仪器一起使用。