Incorporation of Nuclear Magnetic Resonance Spectroscopy Throughout the Chemistry Curriculum

化学（12）核磁共振方法正在通过核磁共振实验被纳入基于发现的化学课程，这些实验是在其他地点开发的，并经过调整以加强以女性为主的人口的教育。被改编的实验来自不同的学科，并发表在《化学教育杂志》上。然而，这些实验也有助于提高课程的整体形象。将获得Anasazi Instruments的傅里叶变换60 MHz核磁共振，以在课程中的不同实验课程中进行实验。在有机化学实验室里，学生们正在用核磁共振来确定他们合成的产物的结构。在第二学期有机课程中进行大型多步骤研究合成项目的学生使用核磁共振来提供明确的证据，证明他们成功完成了学生设计的合成。在分析化学课程中，学生们正在探索核磁共振光谱仪的定量能力，以及改变采集参数对光谱质量的影响。在生物化学课程中，核磁共振被用来探索肽的构象和葡萄糖代谢的动力学。为该项目获得的仪器将与从以前的NSF拨款中购买的仪器一起使用。

Chemistry (12) NMR methodologies are being incorporated into a discovery-based chemistry curriculum by using NMR experiments, developed at other sites, and adapted to enhance the education of a predominantly female population. The experiments being adapted come from various disciplines and have been published in the Journal of Chemical Education. However, the experiments also serve to enhance a larger picture of the curriculum. An Anasazi Instruments Fourier Transform 60 MHz NMR will be acquired to perform the experiments in the different laboratory courses in the curriculum. In the organic chemistry laboratory students are using the NMR to determine the structures of the products they synthesize. Students performing a large multi-step research synthesis project in the second semester organic course are using the NMR to provide clear evidence of the successful completion of the student-designed syntheses. In the analytical chemistry courses, students are exploring the quantitative capabilities of the NMR spectrometer and the influence of changing acquisition parameters on spectral quality. In the biochemistry courses, the NMR is being used to explore peptide conformation and the kinetics of glucose metabolism. The instrumentation obtained for this project is being used in conjunction with instrumentation purchased from previous NSF grants to the department.