ATOL: Collaborative Research: The Deep Scaly Project: Resolving Higher Level Squamate Phylogeny Using Genomic and Morphological Approaches

ATOL：合作研究：深鳞项目：使用基因组和形态学方法解决更高级别的鳞状动物系统发育

• 批准号: 0334923
• 负责人: John Wiens
• 金额: --
• 依托单位: SUNY at Stony Brook
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0334923&HistoricalAwards=false
• 关键词: ATOL; Collaborative; Research; Deep; Scaly

A grant has been awarded to Dr. John Wiens of the State University of New York at Stony Brook to study the evolutionary history of squamate reptiles (lizards and snakes). With more than 7,700 species, squamates are the second largest group of vertebrates after birds. Many critical questions in squamate evolution remain unresolved, such as identification of the most primitive lineage of squamates, the origin of snakes, and the relationships of venomous snakes to other snake lineages. An international team of eight investigators from diverse institutions (Brigham Young University, Field Museum of Natural History, San Diego State University, State University of New York-Stony Brook, University of Adelaide, University of Texas-Austin, and Yale University) will collaborate to resolve squamate relationships. Anatomical data from living and fossil forms will be combined with DNA sequences from 50 genes for 142 representative squamate species. Anatomical data will be obtained using traditional methods and new high resolution X-ray scanning techniques. DNA data will be generated by incorporating new tools and databases from recent vertebrate genome projects. Computer modeling will be used to determine how data from molecular and fossil studies can best be combined to reconstruct evolutionary trees. Wiens will help generate sequence data, anatomical data, and the web-site, and will be solely responsible for computer modeling.Squamates are an important model system in biology, and understanding their evolutionary history is critical for a complete picture of vertebrate evolution and ecology. Venomous snakes pose an important threat to human safety in many parts of the world, and identification is critical for effective treatment. An innovative web-site will allow snakebite victims and medical workers to identify the venomous snakes in their area. Postdoctoral researchers and students will be involved in nearly every aspect of the project, and thus the training of many future biologists and educators will be supported.

纽约州立大学石溪分校的约翰·维恩斯博士获得了一笔资助，用于研究有鳞爬行动物（蜥蜴和蛇）的进化史。 有鳞动物有 ​​7,700 多种，是仅次于鸟类的第二大脊椎动物类群。 有鳞动物进化中的许多关键问题仍未解决，例如有鳞动物最原始谱系的识别、蛇的起源以及毒蛇与其他蛇谱系的关系。 来自不同机构（杨百翰大学、菲尔德自然历史博物馆、圣地亚哥州立大学、纽约州立大学石溪分校、阿德莱德大学、德克萨斯大学奥斯汀分校和耶鲁大学）的八名研究人员组成的国际团队将合作解决有鳞关系。 来自活体和化石形式的解剖数据将与 142 个代表性有鳞动物物种的 50 个基因的 DNA 序列相结合。 解剖数​​据将使用传统方法和新的高分辨率 X 射线扫描技术获得。 DNA 数据将通过整合最近脊椎动物基因组项目的新工具和数据库来生成。 计算机建模将用于确定如何最好地结合分子和化石研究的数据来重建进化树。 维恩斯将帮助生成序列数据、解剖数据和网站，并将全权负责计算机建模。有鳞动物是生物学中的重要模型系统，了解它们的进化历史对于全面了解脊椎动物进化和生态学至关重要。 毒蛇对世界许多地区的人类安全构成重要威胁，识别毒蛇对于有效治疗至关重要。一个创新的网站将允许蛇咬伤受害者和医务人员识别他们所在地区的毒蛇。 博士后研究人员和学生将参与该项目的几乎各个方面，因此将支持许多未来生物学家和教育工作者的培训。