Purchase of an Isothermal Titration and a Differential Scanning Calorimeter
Purchase of an Isothermal Titration and a Differential Scanning Calorimeter
批准号:
0342877
负责人:
Joseph Justice
金额:
$13.38万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2004
资助国家:
美国
项目状态:
已结题
起止时间:
2004-02-01 至 2007-01-31
中文摘要
在化学研究仪器和设施(CRIF)计划的支持下,埃默里大学化学系将获得一台等温滴定热量计和一台差示扫描量热计。该设备将加强一些领域的研究,包括a)蛋白质的工程和结构/功能研究;b)反应物、抑制剂和辅酶与依赖于B12的乙醇胺脱氨酶的结合;c)自组装肽材料的设计;d)模板导向的聚合物合成;以及e)胶体系统的探索。量热法在现代分析化学中是一种非常有用的工具。量热分析用于测量分子相互作用和反应过程中发生的热能(热)交换。因此,它可以提供一种非常可靠和灵敏的方法来确定材料的热力学性质,如液体和固体样品的热容变化。
英文摘要
With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Emory University will acquire an isothermal titration calorimeter and a differential scanning calorimeter. This equipment will enhance research in a number of areas including a) engineering and structure/function studies of proteins; b) binding of reactant, inhibitors and coenzyme to B12-dependent ethanolamine deaminase; c) design of self-assembling peptide materials; d) template-directed polymer synthesis; and e) exploration of colloidal systems. Calorimetry is an extremely useful tool in modern analytical chemistry. Calorimetric analysis is used to measure the thermal energy (heat) exchange that occurs during molecular interactions and reactions. Thus it can provide a very reliable and sensitive method for determining the thermodynamic properties of materials such as changes in heat capacity of liquid and solid samples.
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依托单位:
海外基金