ACT/SGER: Rapid Identification of Biological Warfare Simulants by FTIR

美国约翰霍普金斯大学的Gerald J. Meyer教授正在开发FTIR光谱快速筛选生物战剂的新方法。这个想法是开发多孔底物来过滤和捕获孢子，以便随后用FTIR光谱进行鉴定。这项工作的最终目标是开发一种可靠、敏感的方法来区分生物战剂和普遍存在的自然物种。这项工作将首先利用枯草芽孢杆菌黑变体（一种生物战替代品）开发方法。将使用电化学和反应离子蚀刻技术合成各种类型的多孔衬底。一名女研究生将参与这项利用FTIR快速识别生物战剂的工作。该奖项由美国国家科学基金会和情报界共同支持。数学和物理科学理事会的反恐方法项目支持基础研究和劳动力发展方面的新概念，这些新概念有可能为国家安全做出贡献。

ABSTRACTProfessor Gerald J. Meyer of Johns Hopkins University is developing new methods for the rapid screening of biological warfare agents by FTIR spectroscopy. The idea is to develop porous substrates to filter and trap spores for subsequent identification with FTIR spectroscopy. The eventual goal of this work is to develop a reliable, sensitive method for the discrimination between biological warfare agents and ubiquitous, naturally-occurring species. The work will develop the method using Bacillus Subtilis var. niger first, a biological warfare surrogate. Various types of porous substrates will be synthesized using electrochemical and reactive ion-etching techniques. One female graduate student will be involved in this work on the rapid identification of biological warfare agents by FTIR.This award is supported jointly by the NSF and the Intelligence Community. The Approaches to Combat Terrorism Program in the Directorate for Mathematics and Physical Sciences supports new concepts in basic research and workforce development with the potential to contribute to national security.