RUI: Rapid Injection NMR Studies of Conjugate Addition Reactions of Carbanionic Species

有了这个本科院校研究奖（RUI），有机和高分子计划支持教授克雷格A。Ogle和Michael D. Murphy在北卡罗来纳州，夏洛特，NC的大学化学系中进行了研究。 该项目将应用核磁共振波谱学和快速注入核磁共振技术研究两个非常重要的化学反应，阴离子聚合和有机铜酸酯的加成反应。 虽然这两种反应在科学上和经济上都具有重要意义，但关于它们的机理仍有许多未解之谜。 使用快速NRM技术将允许在这些重要的反应中的活性中间体的结构和性质的测定。在有机和高分子化学计划的支持下，该项目将培训本科生和硕士生使用先进的分析仪器和现代实验设计。 这项研究的潜在经济影响可能是显著的，导致聚合物和制药行业的新产品和新方法。

With this Research in Undergraduate Institutions (RUI) award, the Organic and Macromolecular Program supports the research of Professor Craig A. Ogle and Dr. Michael D. Murphy of the Department of Chemistry at the University of North Carolina, Charlotte, NC. The project will apply NMR spectroscopy and the rapid injection NMR technique to the study of two very important chemical reactions, anionic polymerization and the addition reactions of organocuprates. Although both of these reactions are scientifically significant and highly important economically, there are many consequential unanswered questions concerning their mechanism. The use of the rapid NRM technique will allow the determination of the structure and nature of the reactive intermediates in these important reactions. With support from the Organic and Macromolecular Chemistry Program, this project will train undergraduate and masters students in the use of sophisticated analytical instrumentation and modern experimental design. The potential economic impact of this research could be significant, leading to new products and methodologies in both the polymer and the pharmaceutical industry.