A Mass Spectrometer for Proteomic and Metabolomic Research at the SIUC Multi-User Facility.

SIUC 多用户设施中用于蛋白质组学和代谢组学研究的质谱仪。

• 批准号: 0405819
• 负责人: David Lightfoot
• 金额: --
• 依托单位: Southern Illinois University at Carbondale
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0405819&HistoricalAwards=false
• 关键词: Mass; Spectrometer; Proteomic; Metabolomic; Research

This award provides funds to aid in the purchase of a matrix assisted, laser desorption ionization - time of flight (MALDI-TOF) mass spectrometer (MS) for use in research and training. The major use of such instruments is in determination of the mass of molecules, with accuracy of one-hundredth of an atomic weight. The instrument will be placed in a common facility where it is expected to enable research in a varied areas of biology, including studies of plant drought tolerance and selection of new plant variants, and the bioremediation of brown-earth sites. Other projects expected to make use of the instrument include studies of human proteins involved in cholesterol tolerance, and phylogenetic analysis of genetic diversity among relatively ancient animals, such as sharks, and primitive plants such as mosses, liverworts and hornworts. In addition, the instrument will be used to enhance research training for over 60 undergraduates involved in the Institution's Research Experiences for Undergraduates and Undergraduate Workship programs, as well as being used in training of graduate and postgraduate students.

该奖项提供资金，以帮助购买基质辅助，激光解吸电离-飞行时间（MALDI-TOF）质谱仪（MS）用于研究和培训。 这类仪器的主要用途是测定分子的质量，精确度为原子量的百分之一。 该仪器将被放置在一个共同的设施，预计它将能够在生物学的各个领域进行研究，包括研究植物耐旱性和选择新的植物变种，以及对棕土场地进行生物修复。 预计将利用该仪器的其他项目包括研究与胆固醇耐受有关的人类蛋白质，以及对相对古老的动物（如鲨鱼）和原始植物（如苔藓、地钱和金鱼藻）的遗传多样性进行系统发育分析。 此外，该工具将用于加强对参与该机构本科生研究经验和本科生工作方案的60多名本科生的研究培训，并用于培训研究生和研究生。