Acquisition of Instrumentation for Establishing a Microarray Core

购置用于建立微阵列核心的仪器

• 批准号: 0421189
• 负责人: David Lin
• 金额: --
• 依托单位: Cornell Univ - State: AWDS MADE PRIOR MAY 2010
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0421189&HistoricalAwards=false
• 关键词: Acquisition; Instrumentation; Establishing; Microarray; Core

A grant has been awarded to Cornell University under the direction of Dr. David Lin for partial support of instruments to be utilized in a core microarray facility. These instruments include a standard microarray platform, a spotted array platform, a hybridization station, and a liquid handler. The facility will be housed in the Veterinary Research Tower on the Cornell campus. The ability to monitor the activity of thousands of genes at once has generated new insight into diverse model systems and questions. In addition, the interpretation of microarray data can encourage interactions across disciplines, promoting collaborations among computer scientists, statisticians, and biologists. The rapid rise in microarray use, coupled with the completion of the various Genome Projects, has fueled interest in genomics. This in turn has attracted growing numbers of graduate and undergraduate students to this new field of study. These instruments will supplement existing equipment on campus, enabling a large number of faculty to complete a wide range of microarray experiments. Faculty will be able to: perform standard and spotted array experiments, create custom libraries, print custom chips, hybridize and scan chips, and use available software to analyze the data. Cornell is also developing a Genomics Program of Study aimed at training graduate and undergraduate students. As a component of this program, this Core will position Cornell to successfully provide for the needs of faculty, postdoctoral fellows, graduate students, and undergraduates. This will improve access to and increase the use of state-of-the-art instrumentation for research by scientists across departmental units and is expected to promote interactions among diverse members of the Cornell campus, including biologists, computer scientists and statisticians.

在林大卫博士的指导下，康奈尔大学获得了一笔赠款，用于为核心微阵列设施中使用的仪器提供部分支持。这些仪器包括标准微阵列平台、斑点阵列平台、杂交站和液体处理机。该设施将设在康奈尔大学校园的兽医研究塔内。同时监测数千个基因的活动的能力为不同的模型系统和问题产生了新的见解。此外，对微阵列数据的解释可以鼓励跨学科的互动，促进计算机科学家、统计学家和生物学家之间的合作。微阵列应用的快速增长，加上各种基因组计划的完成，激发了人们对基因组学的兴趣。这反过来又吸引了越来越多的研究生和本科生进入这个新的研究领域。这些仪器将补充校园现有的设备，使大量教师能够完成广泛的微阵列实验。教员将能够：执行标准和斑点阵列实验，创建定制库，打印定制芯片，混合和扫描芯片，并使用可用的软件来分析数据。康奈尔大学还在开发一项基因组学研究计划，旨在培养研究生和本科生。作为这一计划的一部分，这一核心将使康奈尔大学成功地满足教师、博士后研究员、研究生和本科生的需求。这将改善科学家在各部门单位进行研究的机会，并增加对最先进仪器的使用，预计将促进康奈尔大学校园内不同成员之间的互动，包括生物学家、计算机科学家和统计学家。