Acquisition of Instrumentation for Establishing a Microarray Core

在林大卫博士的指导下，康奈尔大学获得了一笔拨款，用于部分支持核心微阵列设施中使用的仪器。这些仪器包括一个标准的微阵列平台，一个斑点阵列平台，一个杂交站和一个液体处理器。该设施将设在康奈尔大学校园的兽医研究大楼内。同时监测数千个基因活动的能力已经对不同的模型系统和问题产生了新的见解。此外，微阵列数据的解释可以鼓励跨学科的互动，促进计算机科学家、统计学家和生物学家之间的合作。微阵列应用的迅速增加，加上各种基因组计划的完成，激起了人们对基因组学的兴趣。这反过来又吸引了越来越多的研究生和本科生进入这一新的研究领域。这些仪器将补充校园现有设备，使大量教师能够完成广泛的微阵列实验。教师将能够：执行标准和点阵实验，创建定制库，打印定制芯片，杂交和扫描芯片，并使用可用的软件来分析数据。康奈尔大学还在开发一个基因组学研究项目，旨在培养研究生和本科生。作为这个项目的一个组成部分，这个核心将使康奈尔大学能够成功地满足教师、博士后、研究生和本科生的需求。这将改善各部门科学家对最先进的研究仪器的使用和使用，并有望促进康奈尔大学校园内不同成员之间的互动，包括生物学家、计算机科学家和统计学家。

A grant has been awarded to Cornell University under the direction of Dr. David Lin for partial support of instruments to be utilized in a core microarray facility. These instruments include a standard microarray platform, a spotted array platform, a hybridization station, and a liquid handler. The facility will be housed in the Veterinary Research Tower on the Cornell campus. The ability to monitor the activity of thousands of genes at once has generated new insight into diverse model systems and questions. In addition, the interpretation of microarray data can encourage interactions across disciplines, promoting collaborations among computer scientists, statisticians, and biologists. The rapid rise in microarray use, coupled with the completion of the various Genome Projects, has fueled interest in genomics. This in turn has attracted growing numbers of graduate and undergraduate students to this new field of study. These instruments will supplement existing equipment on campus, enabling a large number of faculty to complete a wide range of microarray experiments. Faculty will be able to: perform standard and spotted array experiments, create custom libraries, print custom chips, hybridize and scan chips, and use available software to analyze the data. Cornell is also developing a Genomics Program of Study aimed at training graduate and undergraduate students. As a component of this program, this Core will position Cornell to successfully provide for the needs of faculty, postdoctoral fellows, graduate students, and undergraduates. This will improve access to and increase the use of state-of-the-art instrumentation for research by scientists across departmental units and is expected to promote interactions among diverse members of the Cornell campus, including biologists, computer scientists and statisticians.