Mass Spectrometry and Undergraduate Research and Training

质谱分析和本科生研究与培训

• 批准号: 0421581
• 负责人: Matthew Saderholm
• 金额: $ 26.12万
• 依托单位: Berea College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0421581&HistoricalAwards=false
• 关键词: Mass; Spectrometry; Undergraduate; Research; Training

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Berea College will acquire a liquid chromatograph ion trap tandem mass spectrometer (LC/MS). This equipment will enhance research in a number of areas including a) the analysis of synthetic peptides and amino acids; b) the characterization of ginsenosides, active compounds found in ginseng that are potential cancer-fighting agents; c) analysis of polyphosphate samples; and d) the oxidation of high molecular weight alcohols by halogen complexes. Liquid chromatography with mass spectrometric detection (LC/MS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will substantially strengthen scientific research at Berea College, a primarily undergraduate institution. These studies will have a solid impact in the area of biochemistry, medicinal chemistry and synthetic chemistry.

从主要研究仪器（MRI）计划的这一奖项，在伯里亚学院化学系将获得液相色谱离子阱串联质谱仪（LC/MS）。该设备将加强若干领域的研究，包括a）合成肽和氨基酸的分析; B）人参皂苷的特性分析，人参皂苷是人参中发现的活性化合物，是潜在的抗癌剂; c）多磷酸盐样品的分析; d）用卤素络合物氧化高分子量醇。液相色谱-质谱检测（LC/MS）是一种非常强大的技术，用于分离和分析复杂的混合物。这一工具将大大加强伯里亚学院的科学研究，该学院主要是本科院校。 这些研究将在生物化学，药物化学和合成化学领域产生坚实的影响。