Mass Spectrometry and Undergraduate Research and Training
Mass Spectrometry and Undergraduate Research and Training
批准号:
0421581
负责人:
Matthew Saderholm
金额:
$26.12万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2004
资助国家:
美国
项目状态:
已结题
起止时间:
2004-08-01 至 2007-07-31
中文摘要
通过这项来自主要研究仪器(MRI)项目的奖励,伯里亚学院化学系将获得一台液相色谱仪离子阱串联质谱仪(LC/MS)。该设备将加强许多领域的研究,包括a)合成肽和氨基酸的分析;B)人参皂苷的特性,人参中发现的活性化合物是潜在的抗癌剂;C)多磷酸盐样品的分析;d)高分子量醇被卤素络合物氧化。液相色谱质谱检测(LC/MS)是一种非常强大的技术,用于分离和分析复杂的混合物。该仪器将大大加强伯里亚学院的科学研究,这是一个主要的本科生机构。这些研究将在生物化学、药物化学和合成化学等领域产生重要影响。
英文摘要
With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Berea College will acquire a liquid chromatograph ion trap tandem mass spectrometer (LC/MS). This equipment will enhance research in a number of areas including a) the analysis of synthetic peptides and amino acids; b) the characterization of ginsenosides, active compounds found in ginseng that are potential cancer-fighting agents; c) analysis of polyphosphate samples; and d) the oxidation of high molecular weight alcohols by halogen complexes. Liquid chromatography with mass spectrometric detection (LC/MS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will substantially strengthen scientific research at Berea College, a primarily undergraduate institution. These studies will have a solid impact in the area of biochemistry, medicinal chemistry and synthetic chemistry.
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