SBIR Phase II: Nanofluidic Reference Electrode with an Invariant Liquid Junction Potential

SBIR 第二阶段：具有不变液体接界电势的纳流体参比电极

• 批准号: 0422237
• 负责人: Scott Broadley
• 金额: --
• 依托单位: Broadley-James Corporation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0422237&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Nanofluidic; Reference

This Small Business Innovative Research (SBIR) Phase II is for the development of nanofluidic-flowing liquid junction (NFLJ) reference electrodes using nanochannel glass arrays developed by the Naval Research Laboratory. While consuming electrolyte at less than 2 ml/yr, the NFLJ reference electrodes will allow a flow at velocities of over 0.1 cm/sec to impede back diffusion of sample solution into the electrode. A variety of challenging test sample solutions, potentiometric measurements made with NFLJ references varied 0.5 mV with response times of less than 60 seconds while measurements made with conventional reference electrodes varied up to 20 mV with response times of over one hour have already been completed. The NFLJ reference electrode's exceedingly small electrolyte consumption makes possible handheld NFLJ pH sensors with significantly higher precision and longer operational life. The high impedance of NFLJ reference electrodes, when using modern commercial pH electrodes, has no measurable effect on the precision, response time, or span of the pH measurement.The nanochannel glass nanofluidic-flowing liquid junction (NFLJ) adds a new dimension to the design and construction of reference electrodes. The unique ability of the NFLJ design to separate flow volume and flow velocity will provide scientists with a tool for investigating reference electrode behavior as a function of flow, velocity, and resistance. It should help to develop a more fundamental understanding of mass transfer effect on liquid junction potentials. Initial results indicate that velocity is the critical parameter in stabilizing the potential.

这项小型企业创新研究(SBIR)第二阶段用于开发使用海军研究实验室开发的纳米通道玻璃阵列的纳米流体流动液体结(NFLJ)参考电极。当每年消耗不到2毫升的电解液时，NFLJ参比电极将允许超过0.1厘米/秒的速度流动，以阻止样品溶液向电极内的反向扩散。各种具有挑战性的测试样品溶液，使用NFLJ基准进行的电位测量变化0.5 mV，响应时间小于60秒，而使用传统参考电极进行的测量变化高达20 mV，响应时间超过1小时。NFLJ参比电极极小的电解液消耗使手持NFLJ pH传感器具有显著更高的精度和更长的使用寿命。当使用现代商业pH电极时，NFLJ参比电极的高阻抗对pH测量的精度、响应时间或跨度没有可测量的影响。纳米通道玻璃纳米流体流动液体结(NFLJ)为参比电极的设计和构造增加了一个新的维度。NFLJ设计独特的分离流量和流速的能力将为科学家提供一种工具，用于研究作为流量、速度和阻力函数的参比电极行为。这将有助于对液体结势的传质效应有一个更基本的理解。初步结果表明，速度是稳定电势的关键参数。