Center for the Activation and Transformation of Strong Bonds (CATSB)

有了这个化学键合中心（CBC）第一阶段，第二步奖，化学部和数学和物理科学理事会多学科活动办公室共同支持凯伦I的研究。他将领导一个由来自不同机构的12名PI组成的合作小组，研究强化学键的激活和转化。 该CBC汇集了在合成方法学，催化，计算化学和光谱学方面具有专业知识的化学家，旨在开发合成有机材料的高效和环保方法。 这种创新的化学转化方法，其重点是激活强键，而不是官能团修饰，将允许利用从天然气到复杂生物分子的复杂化学原料。 这些研究预计将对大规模工业化学、药物合成和化学品回收产生重大影响。 这个CBC，其重点是现代环境友好的解决方案，以重大意义的历史化学问题，将为学生提供重要的培训，并提高公众对化学作为解决社会问题的驱动力的作用的认识。 化学键合中心旨在集中创新的合作努力，解决一个“大问题”，这将导致化学或化学和其他科学的接口的重大进展，并有可能吸引广泛的科学和公众的兴趣。

With this Chemical Bonding Center (CBC) Phase I, Step II award, the Division of Chemistry and the Office of Multidisciplinary Activities of the Mathematical and Physical Sciences Directorate jointly support the research of Karen I. Goldberg, of the University of Washington, who will lead a collaborative of twelve PIs from a variety of institutions in investigations of the activation and transformation of strong chemical bonds. This CBC brings together chemists with expertise in synthetic methodology, catalysis, computational chemistry, and spectroscopy with the goal of developing efficient and environmentally friendly methods of synthesizing organic materials. This innovative approach to chemical transformations, which focuses on the activation of strong bonds rather than on functional group modification, will allow utilization of chemical feedstocks ranging in complexity from natural gas to complex biological molecules. These investigations are expected to have major impact on large scale industrial chemistry, pharmaceutical synthesis, and chemical recycling. This CBC, with its focus on modern environmentally benign solutions to a historical chemical problem of major significance, will provide important training for students and increase public awareness of the role of chemistry as a driver in solutions of societal problems. Chemical Bonding Centers are designed to focus innovative collaborative efforts that address a "big problem" which will lead to a major advance in chemistry or at the interface of chemistry and other sciences and will have the potential to attract broad scientific and public interest.