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Biomimetic Smart Materials and Sensors

Biomimetic Smart Materials and Sensors
仿生智能材料和传感器
批准号:
0437236
负责人:
Amy Shen
金额:
$10.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2004
资助国家:
美国
项目状态:
已结题
起止时间:
2004-06-15 至 2006-05-31

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中文摘要
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英文摘要
Biomimetic smart materials and sensorsAmy ShenWith the discovery of the plant protein forisome (Knoblauch et al. 2003), a novel nastic non-living, ATP-independent biological material became available to the designer of smart materials for advanced actuating and sensing. The in vitro studies of Knoblauch et al. show that forisomes (1-3 micron wide and 10-30 micron long) can be repeatedly stimulated to contract and expand anisotropically by the application of a pH and calcium concentration shift. Due to their unique features, forisomes have the potential to outperform current smart materials such as ATP-dependent actuators and synthetic hydrogels/polymers as advanced multi-functional smart sensors, valves, and actuators as biomimetic devices. The central goal of this project is to engineer biomimetic smart materials based on ATP-independent plant protein forisomes that will outperform conventional actuators. With many unknowns and challenges, the proposed research is highly exploratory and we will attack these issues using a combination of experiment, modeling, and numerical simulation. The high reward associated with this project comes from establishing the possibility of synthesizing a biomimetic composite with all-in-one, multi-functional (actuation, sensing) component within microdevices and morphing structures. This work will be a major advancement over existing technologies (using, for example, hydrogels, PZT, shape memory alloy) for actuation and sensing in one-piece. Forisome based biomimetic smart materials are important in civil and mechanical applications such as aircraft and small scale vehicle morphing, mechanical adaptive systems, structural noise and vibration control, and will lead to many potential applications in environmental monitoring, drug delivery, biomedical and defense applications.Broader Impact: Research and EducationThe proposed project promises to have a wide-ranging impact not only on fundamental knowledge concerning the synthesis of a new generation biomimetic smart materials for advanced actuating and sensing, but also on the area of other emerging nano-, bio-, and micro-technologies.Each year, PI Amy Shen has set aside two undergraduate research positions in her laboratory to members of Society of Women Engineering at Washington University. Mechanical Engineering junior Elizabeth Henderson has been fabricating microfluidic devices and learning AFM procedure to perform materials characterizations during Spring 2004 and will continue her research on this project starting Fall, 2004. This experience will provide students with the opportunity to learn how to work on a well-defined research project with multidisciplinary interactions in novel materials, fluid mechanics, plant biology, heat transfer, and process design.
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Collaborative Research: Dynamics of Miscible Jets and Drops
  • 批准号:
    1335666
  • 项目类别:
    Standard Grant
  • 资助金额:
    $18.66万
  • 财政年份:
    2013
  • 负责人:
    Amy Shen
  • 依托单位:
Collaborative Research: Laser Treated Sol-Gel Glass for Ultra-High-Quality Photonic Devices
  • 批准号:
    0907638
  • 项目类别:
    Standard Grant
  • 资助金额:
    $29.45万
  • 财政年份:
    2009
  • 负责人:
    Amy Shen
  • 依托单位:
Collaborative Research: MPSA-ENG: Interplay of Biosensing and Locomotion in Confined Microfluidic Environments
  • 批准号:
    0852753
  • 项目类别:
    Standard Grant
  • 资助金额:
    $24.0万
  • 财政年份:
    2008
  • 负责人:
    Amy Shen
  • 依托单位:
CAREER: Confinement and flow effects on synthesis of sol-gel materials
  • 批准号:
    0852471
  • 项目类别:
    Standard Grant
  • 资助金额:
    $37.21万
  • 财政年份:
    2008
  • 负责人:
    Amy Shen
  • 依托单位:
国内基金
海外基金
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基于“活性-代谢组-基因组-SMART”整合策略发掘老鼠簕内生放线菌新型先导化合物
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    地区科学基金项目
  • 资助金额:
    32万元
  • 批准年份:
    2023
  • 负责人:
    卢覃培
  • 依托单位:
特定微环境激活的mRNA翻译(SMART)系统的设计及其免疫治疗应用研究
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  • 批准号:
    --
  • 项目类别:
    --
  • 资助金额:
    105万元
  • 批准年份:
    2022
  • 负责人:
    陈铭
  • 依托单位: