Collaborative Research: MPSA-ENG: Interplay of Biosensing and Locomotion in Confined Microfluidic Environments

该方案利用跨学科的方法来研究C。以及它们对环境变化的感觉反应。C.线虫是生物学中研究最多的模式动物之一，这是由于其遗传易处理性、基因组测序、简单的解剖结构和身体透明性。它也是研究移动性和传感的极好系统。这个项目将使用C。elegans作为一个简单的模型系统的生物体，以获得关键的物理信息，了解之间的相互作用的感觉，运动和环境，将这些信息纳入理论和计算模型的波动运动。这是华盛顿大学的一位机械工程师和纽约大学的一位数学家之间的合作研究项目。这项研究预计将对智能传感和驱动技术产生影响，其结果将作为智能设备开发的基石，可以导致自适应系统和结构的鲁棒设计。

The proposal utilizes an interdisciplinary approach to study the locomotion of C. elegans and their sensory response to environmental variations. C. elegans is one of the mostly studied model animals in biology due to its genetic tractability, sequenced genome, simple anatomy and body transparency. It is also a superb system to study mobility and sensing. This project will use C. elegans as a simple model system of living organisms to obtain critical physical information for understanding the interplay between sensing, locomotion and environment, incorporate this information into theoretical and computational models of undulatory locomotion. This is a collaborative research project between a mechanical engineer at Washington University and a mathematical at the New York University.This research is expected to impact on smart sensing and actuation technology, and the results will serve as building blocks for development of smart devices that can lead to robust design of adaptive systems and structures.