CAREER: A New Approach to Modeling Switchable Interlocked Macro-Molecular Complexes

职业生涯：模拟可切换互锁大分子复合物的新方法

• 批准号: 0449595
• 负责人: Karl Sohlberg
• 金额: --
• 依托单位: Drexel University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0449595&HistoricalAwards=false
• 关键词: CAREER; New; Approach; Modeling; Switchable

Karl Sohlberg of Drexel University is supported by a CAREER award from the Theoretical and Computational Chemistry program within the Division of Chemistry for research involving the development of theoretical methods for modeling stimulus-responsive interlocked macro-molecular complexes. These studies are providing new insights into molecular recognition, self-assembly and multi-stability of these complexex. The work is having a broader impact in the development of functional macromolecular complexes, i.e. nanomachines, and will help in the development of practical and robust design principles for future nano-devices. The work is being carried out in conjunction with an outreach program in the Philadelphia high schools which have a significant population of students who are members of under-represented groups in science.

Drexel University的Karl Sohlberg获得了化学系理论和计算化学项目的职业奖，用于研究开发用于模拟刺激响应互锁大分子复合物的理论方法。 这些研究为这些复合物的分子识别、自组装和多重稳定性提供了新的视角。 这项工作对功能性大分子复合物（即纳米机器）的开发产生了更广泛的影响，并将有助于为未来的纳米器件开发实用和稳健的设计原则。 这项工作正在与费城高中的一个外展计划一起进行，这些高中的学生人数很多，他们是科学领域代表性不足的群体的成员。