CAREER: A New Approach to Modeling Switchable Interlocked Macro-Molecular Complexes

德雷克塞尔大学的卡尔·索尔伯格获得了化学系理论和计算化学项目颁发的职业奖，该奖项的研究涉及为刺激响应型连锁大分子化合物建立模型的理论方法的开发。这些研究为这些络合物的分子识别、自组装和多重稳定性提供了新的见解。这项工作正在对功能高分子复合体的开发产生更广泛的影响，即纳米机械，并将有助于为未来的纳米设备开发实用和可靠的设计原则。这项工作是与费城高中的一项外展计划一起进行的，费城高中有相当数量的学生是科学方面代表性不足的群体的成员。

Karl Sohlberg of Drexel University is supported by a CAREER award from the Theoretical and Computational Chemistry program within the Division of Chemistry for research involving the development of theoretical methods for modeling stimulus-responsive interlocked macro-molecular complexes. These studies are providing new insights into molecular recognition, self-assembly and multi-stability of these complexex. The work is having a broader impact in the development of functional macromolecular complexes, i.e. nanomachines, and will help in the development of practical and robust design principles for future nano-devices. The work is being carried out in conjunction with an outreach program in the Philadelphia high schools which have a significant population of students who are members of under-represented groups in science.