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Collaborative Research: A Novel Approach to Improve the Interfacial Strength of Hydroxyapatite Coated Implants for Orthopedic and Dental Applications

Collaborative Research: A Novel Approach to Improve the Interfacial Strength of Hydroxyapatite Coated Implants for Orthopedic and Dental Applications
合作研究:提高骨科和牙科应用羟基磷灰石涂层植入物界面强度的新方法
批准号:
0500269
负责人:
Mei Wei
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-09-01 至 2010-08-31

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中文摘要
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英文摘要
The objective of the research is to understand the interrelationship between the interface modification and the final performance of the HA coating. Such coatings should have a strong bonding strength, stable interface, superior corrosion resistance and excellent biocompatibility suitable for orthopedic and dental applications. The proposed approach is to modify the Ti alloy surface prior to HA coating. A multifunctional compliant multi-layer will be applied to the surface of the Ti alloy, which consists of a FeCrAl thin film bottom layer, a dense, adherent alpha-alumina subscale, and a nano-whisker alumina top layer. Futhermore, nano HA coatings will be applied onto the surface of the compliant layer using either electrophoresis or biomimetic assembly. Both coating techniques will be explored as model systems for comparison. The proposed project has a broader societal impact on various scientific disciplines. Not only will it deliver a new type of implant material with superior performance for better healthcare, but will also give new insights to overcome the long-standing problems of poor metal-ceramic bonding. The nano-engineered metal surface could also provide a new template for micro-electro-mechanical systems (MEMS) and nano-electro-mechanical systems (NEMS) applications, such as sensors and actuators for harsh environment and drug delivery devices. This project will result in the training of a number of graduate and undergraduate students in the area of biomaterial interface studies, while exposing them to multidisciplinary inter-university (UConn-UCF) collaboration. In addition, we will perform K-12 outreach to get high school teachers and students, especially female and under-representative minorities, excited about engineering research.
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PFI:AIR - TT: Scale-up and Prototyping of Novel Scaffold Fabrication for Bone Regeneration
  • 批准号:
    2002879
  • 项目类别:
    Standard Grant
  • 资助金额:
    $13.41万
  • 财政年份:
    2020
  • 负责人:
    Mei Wei
  • 依托单位:
Symposium BM3, Biomaterials for Regenerative Medicine
  • 批准号:
    1638492
  • 项目类别:
    Standard Grant
  • 资助金额:
    $1.5万
  • 财政年份:
    2016
  • 负责人:
    Mei Wei
  • 依托单位:
PFI:AIR - TT: Scale-up and Prototyping of Novel Scaffold Fabrication for Bone Regeneration
  • 批准号:
    1639914
  • 项目类别:
    Standard Grant
  • 资助金额:
    $20.0万
  • 财政年份:
    2016
  • 负责人:
    Mei Wei
  • 依托单位:
PFI:AIR-TT: Prototyping bioabsorbable composites for bone-fixation applications involving low to medium loads
  • 批准号:
    1414274
  • 项目类别:
    Standard Grant
  • 资助金额:
    $20.0万
  • 财政年份:
    2014
  • 负责人:
    Mei Wei
  • 依托单位:
国内基金
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Research on Quantum Field Theory without a Lagrangian Description
  • 批准号:
    24ZR1403900
  • 项目类别:
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  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    SATOSHI NAWATA
  • 依托单位:
Cell Research
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