NER: Exploratory Research in Molecular Communication between Nanomachines

摘要提案ID：0508506职务：NER：纳米机器之间分子通讯的探索性研究机构：加州大学欧文分校PI姓名：Tutsuya Suda该项目探索了分子通讯作为纳米机器之间通讯解决方案的可能性。 纳米机器是执行简单计算、传感或致动的人造或生物纳米级装置。分子通信是指纳米机器以分子为载体，在短距离（几十微米以内）内进行通信的机制。PI在项目中考虑的分子通信系统包括发送方纳米机器、接收方纳米机器、载体分子以及它们的工作环境。 发送器和接收器包括能够发射和捕获分子的生物（例如细胞或细菌）和生物衍生的（例如从生物系统获取的分子马达或传感器）纳米机器。 载体分子是蛋白质、离子或DNA。 环境是细胞内和细胞间的水溶液。发展分子通讯的研究概念，设计几个可能的分子通讯系统，通过模拟和实验研究评估其可行性，与该领域的研究人员合作，以确定有前途的方案，并制定一个完整的建议，提交给美国国家科学基金会为明年的竞争。建议项目的智力价值和更广泛的影响如下：创建新的研究领域：到目前为止，研究人员专注于了解生物纳米机器和人工创造生物纳米机器的对应物。在这个项目中，P.I.研究分子通信作为纳米机器之间的纳米级通信的解决方案。利用分子作为通讯载体是一项新的研究，创造这种范式转变的研究是智力上的挑战和回报。跨学科研究：该项目是跨学科的，涉及生物技术，纳米技术和信息技术。为生物和纳米技术创造新的应用：通信纳米机器使一系列新的应用成为可能。如果多个纳米机器进行通信，它们可以合作并执行复杂的任务，如纳米尺度传感，分子计算或纳米医学。本研究课题的研究成果，能够创造出如此重要的应用，其影响是广泛的。研究生课程新课程的创造：本课题通过确定新的科学技术领域，对教育产生广泛的影响。 拟议的研究导致在研究生课程水平创建多学科性质的新课程，提供了广泛的纳米尺度科学。

ABSTRACTProposal ID: 0508506Title: NER: Exploratory Research in Molecular Communication between Nano-machinesInstitution: University of California at IrvinePI name: Tutsuya SudaThis project explores the possibility of molecular communication as a solution for communication between nanomachines. Nanomachines are artificial or biological nano-scale devices that perform simple computation, sensing, or actuation. Molecular communication provides a mechanism for nanomachines to communicate over a short distance (adjacent nanomachines to tens of micrometers) using molecules as a communication carrier.The class of molecular communication systems that the PI considers in the project consists of sender nanomachines, receiver nanomachines, carrier molecules, and the environment that these operate in. Senders and receivers include biological (such as cells or bacteria) and biologically derived (such as molecular motors or sensors taken from biological systems) nanomachines that are capable of emitting and capturing molecules. Carrier molecules are proteins, ions, or DNA. The environment is the aqueous solution that is typically found within and between cells.In the project, the P.I. develops research ideas for molecular communication, designs a few possible molecular communication systems, evaluates the feasibility through simulations, empirical studies, collaborates with researchers in the field to identify promising options, and develops a full proposal to submit to NSF for the next year's competition.Intellectual merits and broader impacts of the proposed projects are the following:Creation of new research area: Researchers have so far focused on understanding biological nanomachines and artificially creating counterparts of biological nanomachines. In this project, the P.I. investigates molecular communication as a solution for nano-scale communication between nanomachines. Using molecules as communication carriers is new, and creating such paradigm shifting research is intellectually challenging and rewarding.Interdisciplinary research: The project is interdisciplinary and involves biotechnology, nano technology and information technology. This is intellectually challenging and rewarding.Creation of new applications for bio and nano technologies: Communicating nanomachines enables a new set of applications. If multiple nanomachines communicate, they may cooperate and perform complex tasks such as nano-scale sensing, molecular computing, or nanomedicine. The proposed research enables creation of such important applications, and its impact is broad.Creation of new courses at the graduate program level: The project produces a broad impact on education by identifying a new area of science and technology. The proposed research leads to the creation of new courses of the multidisciplinary nature at a graduate program level that provides a broad scope of nano scale science.