Incorporating Gas-Chromatography/Mass Spectrometry (GC/MS) into a Teaching and Faculty-Mentored Student Research Curriculum

将气相色谱/质谱 (GC/MS) 纳入教学和教师指导的学生研究课程

• 批准号: 0511181
• 负责人: Donald Perry
• 金额: $ 8万
• 依托单位: University of Central Arkansas
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2007-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0511181&HistoricalAwards=false
• 关键词: Incorporating; Gas; Chromatography; Mass; Spectrometry

Chemistry (12)Gas-chromatography/mass spectrometry (GC/MS) is a fundamental instrumental technique used by modern chemists. The Chemistry faculty are adapting experiments from many sources to incorporate GC/MS into their teaching laboratories and faculty-mentored student research program. GC/MS is introduced in the Organic Chemistry two-course sequence as a tool for chemical separations, compound identification, and quantitative work. In Quantitative Analysis, students explore practical GC/MS instrumental concerns and perform more intensive quantification experiments. After completing Quantitative Analysis, students move into several upper division courses, each using GC/MS, such as analysis of a complex organic mixture using GC/MS, FTIR, and NMR in Organic Spectroscopy. In Environmental Chemistry laboratory, students rotate through a series of experiments where they explore aspects of GC/MS in environmental analysis. The final rotation involves student-designed, original investigations of pollutants in local soil/water samples. Students also utilize GC/MS to investigate pesticide/herbicide levels in local soil/water samples as part of a comprehensive environmental management plan in the Environmental Science Practicum. In designated research courses, students use GC/MS to study organic pollution, analyze reaction mixtures of new dendrimers and complex ions to optimize conditions for the synthesis of nanoparticles, investigate DNA damage by removal of nucleobases via hydrolysis, and expand existing methodologies of GC/MS analysis of lipids found in ancient bone/pottery for the analysis of ancient rock paintings (petroglyphs).

化学（12）气相色谱/质谱（GC/MS）是现代化学家使用的基本仪器技术。 化学教师正在调整来自许多来源的实验，将GC/MS纳入他们的教学实验室和教师指导的学生研究计划。 GC/MS在有机化学两门课程中介绍，作为化学分离，化合物鉴定和定量工作的工具。 在定量分析中，学生探索实用的GC/MS仪器问题并进行更密集的定量实验。完成定量分析后，学生将进入几门高年级课程，每门课程都使用GC/MS，例如在有机光谱学中使用GC/MS、FTIR和NMR分析复杂的有机混合物。 在环境化学实验室，学生通过一系列的实验，在那里他们探索GC/MS在环境分析方面旋转。 最后一轮涉及学生设计的，在当地土壤/水样本的污染物的原始调查。 学生还利用GC/MS调查当地土壤/水样中的农药/除草剂水平，作为环境科学实践中综合环境管理计划的一部分。在指定的研究课程中，学生使用GC/MS研究有机污染，分析新树枝状聚合物和络离子的反应混合物以优化纳米颗粒合成条件，通过水解去除核碱基来研究DNA损伤，并扩展现有的GC/MS分析方法古代骨骼/陶器中发现的脂质，用于分析古代岩画（岩画）。