MRI: Acquisition of a Quantitative Microscopy Workstation for Neuroscience and Developmental Biology Research

在Nancy rempel - cloer博士的指导下，格林内尔学院获得了一笔赠款，用于购买定量显微镜工作站，用于学生/教师在神经科学和发育生物学方面的合作研究。显微镜工作站由一台具有共聚焦能力的研究显微镜和一个用于神经解剖分析和三维重建的计算机系统组成。这个定量显微镜工作站将支持格林内尔大学生物学和心理学系的研究，并将用于解决神经科学和发育生物学领域的各种研究问题。定量显微镜工作站将使调查将有助于我们对神经和发育过程的基本问题的理解。新设备将用于研究：1)大鼠杏仁核和前额叶皮层之间的神经解剖学联系；2)秀丽隐杆线虫咽发育的遗传基础；3)鸡胚晶状体形成；4)蜥蜴神经肌肉连接处的突触可塑性；5)调节REM睡眠结构的神经元和神经化学底物。使用显微镜工作站的拟议活动具有广泛而广泛的影响。格林内尔学院大力支持跨学科的研究和教学，这是使用拟议的显微镜工作站的特点。获得这笔资助的设备将跨部门使用，以满足教师及其学生对复杂显微分析的研究需求。学生目前在几个现有的课程中获得了一些显微镜的经验，新的工作站为学生提供了一个宝贵的机会，在更专业的应用中扩展他们的显微镜技能，培训将为他们未来的研究工作提供良好的服务。格林内尔学院在培养未被充分代表的科学群体方面处于领先地位，使用显微镜工作站的教师一直全面参与加强对这些学生的科学教育的项目。该工作站将为神经科学和发育生物学应用的定量显微分析提供先进的工具，从而大大增强学院的基础设施，并将丰富学生的研究培训和学习。

A grant has been awarded to Grinnell College under the direction of Dr. Nancy Rempel-Clower to purchase a quantitative microscopy workstation for collaborative student/faculty research in neuroscience and developmental biology. The microscopy workstation consists of a research microscope equipped with confocal capability and a computerized system for neuroanatomical analysis and 3-dimensional reconstruction. This quantitative microscopy workstation will support research across both the biology and the psychology departments at Grinnell, and will be used to address a variety of research questions in the areas of neuroscience and developmental biology. The quantitative microscopy workstation will enable investigations that will contribute to our understanding of basic questions about neural and developmental processes. The new equipment will be used for investigations of: 1) the neuroanatomical connections between the amygdala and prefrontal cortex in the rat; 2) the genetic basis of the development of the C. elegans pharynx; 3) lens formation in chicken embryos; 4) synaptic plasticity in the lizard neuromuscular junction; and 5) the neuronal and neurochemical substrates that regulate the structure of REM sleep. The proposed activities using the microscopy workstation have wide-ranging broader impacts. Grinnell College strongly supports interdisciplinary research and teaching, which characterizes the use of the proposed microscopy workstation. The equipment acquired with this grant will be used across departments to meet the research needs of faculty and their students for sophisticated microscopic analyses. Students currently gain some experience in microscopy in several existing courses, and the new workstation provides a valuable opportunity for students to expand their microscopy skills in more specialized applications, training that will serve them well in future research endeavors. Grinnell College is a leader in training underrepresented groups in the sciences, and the faculty who will use the microscopy workstation have been integrally involved in programs to enhance science education for these students. The workstation acquired with this grant will significantly enhance the College's infrastructure by providing sophisticated tools for quantitative microscopic analysis for neuroscience and developmental biology applications, and will enrich the research training and learning of a broad cross-section of students.