SGER: The Sensitivity of XANES Spectroscopy to Protein Folding

该SGER奖为一系列初步实验提供资金，以证明X射线吸收近边结构（XANES）光谱法有可能用作观察蛋白质折叠时结构变化的技术。 这些在不同蛋白质环境下进行的测试实验，应该可以证实早期的观察结果，即这种情况是否可以得到最终证明。 如果是这样的话，那么XANES光谱学可能成为蛋白质折叠实验研究的有力工具，并在生物物理学的许多领域产生广泛的影响。

This SGER award provides funding for a series of preliminary experiments to demonstrate that X-ray Absorption Near-Edge Structure (XANES) spectroscopy has the potential to be used as a technique for observing changes in structure as proteins fold. These test experiments, conducted under different protein environments, should confirm whether an earlier observation that this is the case can be conclusively proven. If so, then XANES spectroscopy could potentially become a powerful tool in the experimental study of protein folding and have a broad impact across many areas of biological physics.