SGER: The Sensitivity of XANES Spectroscopy to Protein Folding

这项SGER奖为一系列初步实验提供资金，以证明X射线吸收近边缘结构(XANES)光谱有潜力用作观察蛋白质折叠时结构变化的技术。这些测试实验是在不同的蛋白质环境下进行的，应该可以确认之前的观察结果是否可以得到确凿的证明。如果是这样的话，XANES光谱学可能会成为蛋白质折叠实验研究的有力工具，并对生物物理学的许多领域产生广泛的影响。

This SGER award provides funding for a series of preliminary experiments to demonstrate that X-ray Absorption Near-Edge Structure (XANES) spectroscopy has the potential to be used as a technique for observing changes in structure as proteins fold. These test experiments, conducted under different protein environments, should confirm whether an earlier observation that this is the case can be conclusively proven. If so, then XANES spectroscopy could potentially become a powerful tool in the experimental study of protein folding and have a broad impact across many areas of biological physics.