SGER: Self-Assembled Guanosine Based Hybrid Single Molecular Electronic Devices

SGER：自组装鸟苷基混合单分子电子器件

• 批准号: 0533960
• 负责人: Arup Neogi
• 金额: --
• 依托单位: University of North Texas
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0533960&HistoricalAwards=false
• 关键词: SGER; Self; Assembled; Guanosine; Based

Our objective in the proposed exploratory research program is to develop:i. Nanoscale molecular electronic diodes based on self-assembled modified guanosinesemiconductor immobilized on a GaN semiconductor substrate. This effort includes optimization of the material characteristics to improve device performance by increasing the length of a single molecular chain of guanosine. It will enable large-scale fabrication of nanoscale molecular electronic device using conventional photolithography techniques. ii. Field-effect transistor or photo-detectors on GaN with enhanced efficiency in the ultraviolet visible region. We will also extend this device functionality to examine electrochemical properties of double-stranded DNA by altering DNA base-pairing and incorporating synthetic nucleotides to DNA.Intellectual merit and Broader Impact:Among biomolecules, DNA has a fundamental role in biological processes. The combination ofmolecular biology (for engineering DNA with the desired functional and/or self-assemblingproperties) and microelectronic technology (for device fabrication) thus becomes the tool to realize a new class of nanoelectronic element. Since this is a vastly interdisciplinary project, we intend to combine and build upon our strength in prior achievements of development and characterization of GaN based materials/devices and tailoring oligonucleotide molecules along with our collaborator's established capability of conjugating functionalized polymers to biomolecules at Michigan Molecular Institute. This team will include a student, who will be exposed to all phases of this multifaceted project. At UNT there is currently an NSF Research Experience for Undergraduates program that will be enhanced by this proposed research. The PI will offer a focused course on soft condensed matter physics at UNT based on the success of the proposed work.

在我们提出的探索性研究计划中，我们的目标是：i.基于固定在GaN半导体衬底上的自组装修饰鸟苷半导体，开发纳米级分子电子二极管。这项工作包括优化材料特性，通过增加鸟苷的单分子链长度来改善器件性能。它将使使用传统光刻技术大规模制造纳米级分子电子器件成为可能。二、GaN上的场效应晶体管或光电探测器在紫外可见光区具有更高的效率。我们还将扩展这一设备的功能，通过改变DNA碱基配对并将合成的核苷酸加入到DNA中来检测双链DNA的电化学性质。智能优势和更广泛的影响：在生物分子中，DNA在生物过程中具有基础作用。因此，分子生物学(用于设计具有所需功能和/或自组装特性的DNA)和微电子技术(用于器件制造)的结合成为实现新型纳米电子元件的工具。由于这是一个广泛的跨学科项目，我们打算将我们在GaN基材料/器件的开发和表征以及定制寡核苷酸分子方面的先前成就与我们的合作者在密歇根分子研究所建立的将功能化聚合物与生物分子偶联的能力结合起来，并在此基础上继续发展。这个团队将包括一名学生，他将接触到这个多方面项目的所有阶段。在UNT，目前有一个面向本科生的NSF研究体验计划，该计划将通过这项拟议的研究而得到加强。在拟议工作取得成功的基础上，国际和平研究所将在UNT开设一门关于软凝聚态物理的重点课程。