Gordon Research Conference: Protein Folding Dynamics and Gordon-Kenan Graduate Seminar to be held on January 6-13, 2006 in Ventura, California
Gordon Research Conference: Protein Folding Dynamics and Gordon-Kenan Graduate Seminar to be held on January 6-13, 2006 in Ventura, California
批准号:
0546926
负责人:
Charles Brooks
金额:
$1.6万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-09-01 至 2006-08-31
中文摘要
PI将组织蛋白质折叠动力学戈登研究会议和蛋白质折叠动力学第一戈登-凯南研究生研究研讨会,这是一个研究生和博士后研讨会,讨论蛋白质折叠的方法和模型。会议将于2006年1月6日至13日在加州文图拉的哈伯敦福朋喜来登酒店举行。 蛋白质折叠是一个多学科的研究领域,解决生物学中的基本问题之一。理解折叠的动力学和能量特征是阐明蛋白质功能和设计问题的关键。因此,很少有其他领域看到物理和生物科学如此成功的融合。越来越多的研究将实验和理论结合在一起,这种结合正在推进我们对折叠过程的基本定量理解。技术和理论的进步已经改变了我们对蛋白质折叠发生方式的看法。快速事件可以在接近全原子分子动力学模拟的时间尺度上通过实验观察到。新的,复杂的“简单”的蛋白质模型允许合奏动力学进行采样和实验比较。这个戈登研究会议蛋白质折叠动力学,是一个相对较新的会议,专门把实验和理论结合在一起,探索该领域的进展。戈登-凯南研究生研究研讨会在蛋白质折叠动力学是一个新的会议正在组织作为卫星的GRC蛋白质折叠动力学。该研讨会将作为研究生和博士后科学家发展当前技术,理论和蛋白质折叠模型背景的场所。年轻和发展中的科学家的参与和包容代表了我们愿景的一个关键目标,即为这个充满活力的多学科研究领域提供科学家,这些科学家广泛基于实验蛋白质折叠方法以及模型和理论,为解释该领域的实验提供基础。本次会议由生物科学理事会分子和细胞生物科学部的分子生物物理学计划以及数学和物理科学理事会的物理学部门支持。
英文摘要
The PI will organize a Gordon Research Conference on Protein Folding Dynamics and the first Gordon-Kenan Graduate Research Seminar in Protein Folding Dynamics, which is a workshop for graduate students and postdocs addressing the methods and models of protein folding. The meetings will take place at the Four Points Sheraton Harbortown, Ventura, California, January 6-13, 2006. Protein folding is a multidisciplinary area of research addressing one of the fundamental problems in biology. Understanding the dynamical and energetic features of folding are keys to elucidating issues of protein function and design. Consequently, few other fields have seen such a successful blend of physical and biological sciences. Progressively, more studies that bring together experiment and theory are being published, and this combination is advancing our fundamental quantitative understanding of the folding process. Technological and theoretical advances have altered our view of the how protein folding occurs. Fast events can be observed experimentally on timescales that approach those accessible by all-atom molecular dynamics simulations. New, sophisticated "simple" models of proteins allow ensemble kinetics to be sampled and compared to experiment.This Gordon Research Conference in Protein Folding Dynamics, is a relatively new conference, set up to specifically bring experiment and theory together to explore advances in the field. The Gordon-Kenan Graduate Research Seminar in Protein Folding Dynamics is a new meeting being organized as a satellite to the GRC in Protein Folding Dynamics. This workshop will serve as a venue for graduate students and postdoctoral scientists to develop background on current techniques, theories and models of protein folding. The involvement and inclusion of young and developing scientists represents a key objective in our vision to provide this vibrant multi-disciplinary research area with scientists who are broadly based in both experimental protein folding methodologies and the models and theories that provide a basis for the interpretation of experiment in this field. This conference is supported by the Molecular Biophysics Program in the Division of Molecular and Cellular Biosciences in the Directorate for Biological Sciences and the Division of Physics in the Mathematical and Physical Sciences Directorate.
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会议论文
Multiscale Modeling and Enhanced Sampling of Protein-Protein Recognition
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批准号:1506273
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项目类别:Continuing Grant
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资助金额:$121.94万
-
财政年份:2015
-
负责人:Charles Brooks
-
依托单位:
Multi-scale Studies of pH-mediated Viral Capsid Dynamics and Mechanics
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批准号:1121575
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项目类别:Continuing Grant
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资助金额:$67.72万
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财政年份:2011
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负责人:Charles Brooks
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依托单位:
SCI: Collaborative Research: DAPLDS - a Dynamically Adaptive Protein-Ligand Docking System based on Multi-Scale Modeling
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批准号:0836458
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项目类别:Standard Grant
-
资助金额:$13.25万
-
财政年份:2008
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负责人:Charles Brooks
-
依托单位:
Polarizable Force Fields for Biological Molecules: Applications to Integral Membrane Ion Channels
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批准号:0836459
-
项目类别:Continuing Grant
-
资助金额:$34.1万
-
财政年份:2008
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负责人:Charles Brooks
-
依托单位:
2008 Gordon Research Conference on Protein Folding Dynamics to be held at the Four Points Sheraton Harbortown, Ventura, California from January 6-11, 2008.
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批准号:0751556
-
项目类别:Standard Grant
-
资助金额:$1.5万
-
财政年份:2007
-
负责人:Charles Brooks
-
依托单位:
SCI: Collaborative Research: DAPLDS - a Dynamically Adaptive Protein-Ligand Docking System based on Multi-Scale Modeling
-
批准号:0506316
-
项目类别:Standard Grant
-
资助金额:$26.77万
-
财政年份:2005
-
负责人:Charles Brooks
-
依托单位:
Polarizable Force Fields for Biological Molecules: Applications to Integral Membrane Ion Channels
-
批准号:0413858
-
项目类别:Continuing Grant
-
资助金额:$74.28万
-
财政年份:2004
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负责人:Charles Brooks
-
依托单位:
Conference: Energy Landscapes of Proteins, Glasses and Clusters: Dynamics, Folding, Function and Prediction, to be held April 1-5, 2001 in San Diego, CA
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批准号:0091839
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项目类别:Standard Grant
-
资助金额:$1.0万
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财政年份:2001
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负责人:Charles Brooks
-
依托单位:
Dynamic Bandwidth Allocation for ATM Networks
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批准号:9614909
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项目类别:Standard Grant
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资助金额:$1.8万
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财政年份:1996
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负责人:Charles Brooks
-
依托单位:
Postdoc: Novel Computational Approaches to Free Energy Perturbation Calculations
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批准号:9503998
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项目类别:Standard Grant
-
资助金额:$3.95万
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财政年份:1995
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负责人:Charles Brooks
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依托单位:
Computational Studies of Peptide Folding Mechanisms
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批准号:9108780
-
项目类别:Standard Grant
-
资助金额:$3.36万
-
财政年份:1991
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负责人:Charles Brooks
-
依托单位:
Acquisition and Support of Computational Hardware at Carnegie Mellon University
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批准号:8822064
-
项目类别:Continuing Grant
-
资助金额:$13.15万
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财政年份:1989
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负责人:Charles Brooks
-
依托单位:
Acquisition of a Computer Graphics System
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批准号:8606004
-
项目类别:Standard Grant
-
资助金额:$6.5万
-
财政年份:1986
-
负责人:Charles Brooks
-
依托单位:
国内基金
海外基金
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