Multiple Metal-Carbon Bonds, Metallacycles, and Catalytic Reactions

多重金属-碳键、金属环和催化反应

• 批准号: 0554734
• 负责人: Richard Schrock
• 金额: --
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-15 至 2010-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0554734&HistoricalAwards=false
• 关键词: Multiple; Metal; Carbon; Bonds; Metallacycles

Professor Richard R. Shrock of the Massachusetts Institute of Technology is supported by the Inorganic, Bioinorganic and Organometallic Chemistry program to develop synthetic and mechanistic aspects of asymmetric olefin metathesis with imido alkylidene complexes of molybdenum and tungsten. Fundamental reactions of related unbridged M=M dinuclear complexes, formed from catalyst decomposition, are also being explored. Mapping energy surfaces for formation and rearrangement of metallacyclobutane intermediates that are central to olefin metathesis reactions is a goal of this program.Somewhat like a square dance partner change, olefin metathesis involves combining two olefins to yield two new olefins in an economically efficient manner. High oxidation state organometallic chemistry of early transition metal complexes is being investigated in order to improve their catalytic capabilities. These reagents are important for catalytic transformations of organic substrates, particularly those needed for the synthesis of chiral pharmaceutical products.

Richard R.马萨诸塞州理工学院的Shrock得到无机、生物无机和有机化学项目的支持，以开发钼和钨的亚氨基亚烷基络合物的不对称烯烃复分解的合成和机理方面。 由催化剂分解形成的相关非桥连M=M双核配合物的基本反应也正在探索中。 映射能量表面的形成和重排的金属环丁烷中间体是中心的烯烃复分解反应是这个程序的目标。有点像一个广场舞的合作伙伴的变化，烯烃复分解涉及结合两个烯烃，以产生两个新的烯烃在经济有效的方式。为了提高前过渡金属配合物的催化性能，人们正在研究其高氧化态的有机金属化学。这些试剂对于有机底物的催化转化是重要的，特别是那些合成手性药物产品所需的催化转化。