Innovations through Computational Sciences

通过计算科学进行创新

• 批准号: 0556308
• 负责人: Sandra Harpole
• 金额: --
• 依托单位: Mississippi State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2009-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0556308&HistoricalAwards=false
• 关键词: Innovations; through; Computational; Sciences

The proposal submitted by Mississippi State University (MSU) aims at establishing national prominence in computational sciences research by building on the State's existing strengths in high performance computing. Its specific goals are: (1) increase the State's research capacity by (a) recruit ~12 outstanding faculty with competitive start-up packages (~$100K/year), (b) support and mentor new and existing faculty in interdisciplinary computational sciences research, and (c) enhance the computational sciences infrastructure with new equipment and support staff; (2) expand the collaboration among MRC institutions and outside laboratories; (3) increase opportunities for women and underrepresented groups in the selected research areas; (4) increase the number of participating graduate students and their interface with K-12 students and teachers; and (5) foster state economic development through new intellectual property and its commercialization.Three interrelated areas of computational sciences will be the focus of the project: (1) computational biology, (2) computational chemistry, and (3) biosystem simulation. Computational biology research will focus on the development of novel algorithms to store, retrieve, and analyze data. Computational chemistry research aims at improving the understanding of small molecules and their interactions with large molecule biological targets. Research on biosystem simulation is expected to contribute to a comprehensive understanding of complex physiological processes that cannot be easily measured, and to their incorporation into integrative, whole-body models. The theme for this project, computational sciences, builds on previous research investments, the links among the three research areas, and the potential for commercialization. Therefore, the proposed scope of work will allow the State to advance research and strengthen collaboration among its largest research universities, including (1) Jackson State University (JSU) through its Army High Performance Computing Research Center, (2) Mississippi State University (MSU) with the High Performance Computing Laboratory, (3) University of Mississippi (UM) via the Center for Supercomputing Research, and (4) University of Southern Mississippi (USM) with its DoD HPC Major Shared Resource Center at Stennis Space Center, and its High Performance Visualization Lab. An education and outreach initiative will focus on recruiting and retaining promising students in computational majors. The approach is to expand existing programs and to develop new components, which include partnerships between institutions of higher learning, and to provide secure pathways for students in computational science majors with intervention at various levels from high school to graduate school.

密西西比州立大学（MSU）提交的提案旨在通过建立该州在高性能计算方面的现有优势，在计算科学研究方面建立国家突出地位。它的具体目标是：(1)通过(a)招募~12名优秀的教师，提供有竞争力的启动包（~ 10万美元/年）来增加国家的研究能力，(b)支持和指导跨学科计算科学研究的新教师和现有教师，以及(c)用新的设备和支持人员加强计算科学基础设施；(2)扩大MRC机构与外部实验室的合作；(3)在选定的研究领域增加妇女和代表性不足群体的机会；(4)增加研究生的参与人数，增加他们与K-12学生和教师的接触；(5)通过新知识产权及其商业化促进国家经济发展。计算科学的三个相互关联的领域将是该项目的重点：(1)计算生物学，(2)计算化学，(3)生物系统模拟。计算生物学的研究将集中于开发新的算法来存储、检索和分析数据。计算化学研究旨在提高对小分子及其与大分子生物靶点相互作用的理解。生物系统模拟的研究有望有助于对难以测量的复杂生理过程的全面理解，并将其纳入综合的全身模型。该项目的主题是计算科学，它建立在以前的研究投资、三个研究领域之间的联系以及商业化潜力的基础上。因此，拟议的工作范围将允许该州推进研究并加强其最大的研究型大学之间的合作，包括(1)杰克逊州立大学（JSU）通过其陆军高性能计算研究中心，(2)密西西比州立大学（MSU）与高性能计算实验室，(3)密西西比大学（UM）通过超级计算研究中心，(4)南密西西比大学（USM）及其在斯坦尼斯航天中心的国防部高性能计算专业共享资源中心及其高性能可视化实验室。一项教育和推广计划将侧重于招聘和留住计算机专业有前途的学生。方法是扩大现有的项目，并开发新的组成部分，其中包括高等院校之间的合作关系，并为计算科学专业的学生提供安全的途径，从高中到研究生院的各个层次的干预。