MRI: Acquisition of a High Resolution MALDI-TOF Mass Spectrometer for Chemical Research

MRI：购买高分辨率 MALDI-TOF 质谱仪用于化学研究

• 批准号: 0619770
• 负责人: Russell Schmehl
• 金额: $ 39.43万
• 依托单位: Tulane University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0619770&HistoricalAwards=false
• 关键词: MRI; Acquisition; Resolution; MALDI; TOF

With support from the Major Research Instrumentation (MRI) Acquisition Program, the Department of Chemistry at Tulane University will acquire a Matrix-assisted Laser Desorption Ionization Time of Flight Mass Spectrometer (MALDI-TOF). The spectrometer will be used to investigate a variety of areas including synthesis of polymer macrocycles, characterization of enzymatic polymerizations, mechanistic studies of enzymes, organometallic catalysts, and polymetallic light harvesting ensembles of transition metal complexes. Matrix assisted laser desorption ionization (MALDI) time of flight (TOF) mass spectrometry is the technique of choice for characterization of synthetic and natural macromolecules. It allows molecular weights of large molecules to be determined accurately and structures to be deduced. The instrument will be dedicated to serving Tulane students, and neighboring Loyola, Xavier and Dillard universities. It will be used in a variety of education and service activities including the education of students in instrumental analysis and biochemistry courses.

在主要研究仪器（MRI）获取计划的支持下，杜兰大学化学系将获得一台矩阵辅助激光解吸电离飞行时间质谱仪（MALDI-TOF）。该光谱仪将用于研究各种领域，包括聚合物大环的合成，酶聚合的表征，酶的机理研究，有机金属催化剂，以及过渡金属配合物的多金属光捕获集合。基质辅助激光解吸电离（MALDI）飞行时间（TOF）质谱法是合成和天然大分子表征的首选技术。它可以精确地测定大分子的分子量，并推导出其结构。这台乐器将专门为杜兰大学以及邻近的洛约拉大学、泽维尔大学和迪拉德大学的学生服务。它将用于各种教育和服务活动，包括对学生进行仪器分析和生物化学课程的教育。