Community Annotation Database for Magnaporthe grisea and its Interactions with Rice

稻瘟病菌是稻瘟病的病原菌，是水稻生产的主要制约因素。更好地了解水稻对稻瘟病菌的分子反应将为设计更持久的抗病水稻品种提供新的机会。稻瘟病菌之所以成为阐明植物与真菌相互作用的分子机制的模式系统，有多种重要原因。稻瘟病菌不仅杀死世界各地的水稻，而且一些菌株还攻击其他主要的谷物和牧草。这种感染方式基本上类似于许多真菌病原体，而且比许多真菌，如霉菌和锈菌更容易研究，因为它可以在特定的培养基上培养，以便可以广泛地研究感染过程的早期阶段。此外，水稻和稻瘟病菌的基因组序列都是可用的。这笔赠款将向社区开放MGOS数据库(www.mgodb.org)，以便对基因进行注释，提交微阵列数据，并纳入其他相关的水稻-稻瘟病菌数据。为此，将对界面和数据库进行升级，以提供提交数据和加强数据整合的工具。MGOS的工作人员将对公开注释的基因进行整理，以确保完整性，并与水稻-稻瘟病菌社区互动，以鼓励参与。MGOS基于网络的数据库，包括精选的基因和支持证据，将为所有研究宿主-病原体相互作用的研究人员提供一个极好的资源。MGOS是为便于探索信息而设计的，因此它为研究人员和学生研究水稻与稻瘟病菌的相互作用提供了一个极好的媒介。为了利用这一公共资源造福高中生，MGOS将提供有关水稻和稻瘟病菌相互作用的广泛教程。亚利桑那大学有一项备受认可的计划，名为“植物基因组学教师实习计划”(TIPG)，旨在为任职前和在职的生物学教师提供大学植物基因组学实验室经验。将为TIPG教师举办为期一天的研讨会，以传播教学材料，并就如何使教学令高中生兴奋提出建议。

The fungus Magnaporthe grisea causes the rice blast disease and is a leading constraint to rice production. A better understanding of the molecular response of rice to M. grisea would provide new opportunities to engineer more durable resistant rice cultivars. There are multiple significant reasons why M. grisea has emerged as a model system for elucidating the molecular mechanism governing plant-fungal interactions. M. grisea not only kills rice throughout the world, but some strains attack other major cereals and grasses. The mode of infection is fundamentally similar to many fungal pathogens, and is easier to study then many fungi such as mildews and rust since it can be cultured on defined media so that early stages of the infection process can be studied ex planta. Furthermore, the genomic sequence is available for both rice and M. grisea. This grant will open the MGOS database (www.mgosdb.org) to the community for annotation of genes, submission of microarray data, and incorporation of other relevant rice-M.grisea data. Towards this end, the interface and database will be upgraded to provide tools for submission and enhanced integration of data. The MGOS staff will curate the publicly annotated genes to ensure integrity and interact with the rice-M.grisea community to encourage involvement. The MGOS web-based database with curated genes and supporting evidence will provide an excellent resource to all researchers of host-pathogen interactions. MGOS is being designed for easy exploration of the information, so it provides an excellent medium for the study of rice-M.grisea interactions by both researchers and students. In order to capitalize on this public resource for the benefit of high school students, extensive tutorials on the interactions of rice and M. grisea will be made available from MGOS. The University of Arizona has a highly recognized program called "Teacher Internships in Plant Genomics Program" (TIPG) which is designed to provide pre-service and in-service biology teachers with university-based lab experience in plant genomics. A one-day workshop for the TIPG teachers will be held to disseminate the instructional material and to elicit advice on how to make the instructions exciting to high school students.