NIRT: Active Nanophotofluidic Systems for Single Molecule/Particle Analysis
NIRT:用于单分子/颗粒分析的活性纳米光流控系统
基本信息
- 批准号:0708599
- 负责人:
- 金额:$ 100万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-09-01 至 2012-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
0708599Erickson, David C.This NSF-NIRT award is centered around the active integration of nanophotonics, nanofluidics, nanomaterials and single molecule physics into a new field, refered herein as ''Nanophotofluidics''. The assembled team consists of researchers from Cornell University and the University of Rochester bringing distinct individual expertise to form the integrated, multidisciplinary research program to exploit the extremely high optical intensities achievable in our newly developed 50nm wide exposed mode ?slot waveguides? to perform optofluidic tweezing and propulsion (by exploiting polarization and scattering/adsorption forces) and demonstrate a series of new active nanoscopic single molecule and multi-particle analytical tools. Intellectual MeritThis program is divided into three focused research areas: 1) develop a better fundamental understanding of the coupling of electromagnetics and hydrodynamics on the nanoscale to demonstrate the core elements of a broader nanophotofluidic transport architecture, 2) demonstrate the most resolute separation mechanism developed to date, and 3) develop a new mechanism for investigating single protein folding dynamics in solution. Broader Impacts Integrating photonic elements as active components in micro- and nano-fluidic devices represents a largely unexplored area that could have significant impact that could be extended into a broad new class of photonically driven microfluidic devices where rapid, network based particle manipulation is performed using the high-speed components already developed by the telecommunications industry. Such platforms may find application in emerging fields such as nano-assembly (offering all the advantages of optical tweezing but more rapidly and with sub-wavelength precision). A fundamental part of this program is an outreach and education strategy consisting of: 1) The development of a series of integrated educational units distributed to K-12 classrooms nationwide through the Cornell Main Street Science program and 2) An interdisciplinary nanoscience and engineering seminar series for the upstate New York area. This seminar series will attract attendees from both universities as well as undergraduate institutions in upstate New York. The talks will also be posted on a dedicated website for download. Students from the target institutions will also be given the opportunity to post questions on a dedicated website which will be answered directly by the speaker or the PIs.This research is well aligned with both NSF Active Nanostructures and Nanoscale Devices and System Architecture research themes.
该NSF-NIRT奖的核心是将纳米光子学、纳米流体、纳米材料和单分子物理积极地整合到一个新的领域,在这里被称为“纳米光流体”。组建的团队由来自康奈尔大学和罗切斯特大学的研究人员组成,他们带来了独特的个人专业知识,形成了综合的、多学科的研究计划,以利用我们新开发的50 nm宽曝光模式?缝隙波导?可以实现的极高的光强度。进行光流体钳制和推进(利用极化和散射/吸附力),并展示一系列新的活性纳米单分子和多粒子分析工具。智力价值该计划分为三个重点研究领域:1)在纳米尺度上更好地了解电磁学和流体动力学的耦合,以展示更广泛的纳米光流体传输体系的核心元素;2)展示迄今开发的最坚定的分离机制;以及3)开发一种新的机制,用于研究单一蛋白质在溶液中的折叠动力学。更广泛的影响将光子元件作为活性成分集成在微纳流体设备中是一个基本上未被探索的领域,可能会产生重大影响,可能扩展到广泛的新型光子驱动微流体设备,在这些设备中,使用电信行业已经开发的高速组件来执行快速的、基于网络的粒子操纵。这样的平台可能会在新兴领域找到应用,如纳米组装(提供光学镊子的所有优势,但更快,具有亚波长精度)。该计划的一个基本部分是外展和教育战略,包括:1)开发一系列综合教育单元,通过康奈尔大街科学计划分发给全国的K-12教室;2)为纽约州北部地区举办一系列跨学科纳米科学和工程研讨会。这一系列研讨会将吸引来自两所大学以及纽约州北部本科院校的与会者。讲座还将发布在一个专门的网站上供下载。来自目标机构的学生也将有机会在一个专门的网站上发布问题,由演讲者或PIS直接回答。这项研究与NSF主动纳米结构和纳米尺度器件和系统架构的研究主题很好地结合在一起。
项目成果
期刊论文数量(0)
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科研奖励数量(0)
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David Erickson其他文献
FINANCIAL BENEFIT OF A TELE-INTENSIVIST PROGRAM TO A RURAL HEALTH SYSTEM
- DOI:
10.1378/chest.132.4_meetingabstracts.444 - 发表时间:
2007-10-01 - 期刊:
- 影响因子:
- 作者:
Edward T. Zawada;Pat Herr;David Erickson;John Hitt - 通讯作者:
John Hitt
Molecular Nanotweezers; True Nano-Manipulation of Macromolecules and Other Bioparticles
- DOI:
10.1016/j.bpj.2012.11.3717 - 发表时间:
2013-01-29 - 期刊:
- 影响因子:
- 作者:
Robert Hart;Bernardo Cordovez;David Erickson - 通讯作者:
David Erickson
Optofluidics for energy applications
用于能源应用的光流体学
- DOI:
10.1038/nphoton.2011.209 - 发表时间:
2011-09-11 - 期刊:
- 影响因子:32.900
- 作者:
David Erickson;David Sinton;Demetri Psaltis - 通讯作者:
Demetri Psaltis
The lysosomal disease network
- DOI:
10.1016/j.ymgme.2012.11.073 - 发表时间:
2013-02-01 - 期刊:
- 影响因子:
- 作者:
Brenda Diethelm-Okita;David Erickson;James Cloyd;Elsa Shapiro;Chester Whitley - 通讯作者:
Chester Whitley
A Canadian Simulation Model for Major Depressive Disorder: Study Protocol
- DOI:
10.1007/s41669-024-00481-y - 发表时间:
2024-03-26 - 期刊:
- 影响因子:2.100
- 作者:
Shahzad Ghanbarian;Gavin W. K. Wong;Mary Bunka;Louisa Edwards;Sonya Cressman;Tania Conte;Sandra Peterson;Rohit Vijh;Morgan Price;Christian Schuetz;David Erickson;Linda Riches;Ginny Landry;Kim McGrail;Jehannine Austin;Stirling Bryan - 通讯作者:
Stirling Bryan
David Erickson的其他文献
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{{ truncateString('David Erickson', 18)}}的其他基金
I-Corps: High Efficiency Rapid Magnetic Erythrocyte Separator
I-Corps:高效快速磁性红细胞分离器
- 批准号:
1837864 - 财政年份:2018
- 资助金额:
$ 100万 - 项目类别:
Standard Grant
PFI:BIC: Nutriphone: A Nanoparticle-based Optical Contrast Assay to Monitor Vitamin and Micro-nutrient Levels Uisng Smartphones
PFI:BIC:Nutriphone:基于纳米粒子的光学对比测定法,使用智能手机监测维生素和微量营养素水平
- 批准号:
1430092 - 财政年份:2014
- 资助金额:
$ 100万 - 项目类别:
Standard Grant
INSPIRE Track 2: Public Health, Nanotechnology, and Mobility (PHeNoM)
INSPIRE 轨道 2:公共卫生、纳米技术和移动性 (PHeNoM)
- 批准号:
1343058 - 财政年份:2014
- 资助金额:
$ 100万 - 项目类别:
Standard Grant
AIR Option 1: Technology Translation: KS-Detect: A complete "sample-in, answer-out" solution to the diagnosis of Kaposi's Sarcoma
AIR 选项 1:技术翻译:KS-Detect:卡波西肉瘤诊断的完整“样本输入、应答输出”解决方案
- 批准号:
1343411 - 财政年份:2013
- 资助金额:
$ 100万 - 项目类别:
Standard Grant
LABT-Learning Assistants Become Teachers
LABT-学习助理成为老师
- 批准号:
1136412 - 财政年份:2012
- 资助金额:
$ 100万 - 项目类别:
Continuing Grant
IDR: Self-Reliant, Autonomous Microsystems for Biophysical Monitoring of Small Animals (Lab-on-a-Bird)
IDR:用于小动物生物物理监测的自力更生、自主微系统(鸟类实验室)
- 批准号:
1014891 - 财政年份:2010
- 资助金额:
$ 100万 - 项目类别:
Standard Grant
CAREER: Optofluidics - Fusing Microfluidics and Photonics
职业:光流控 - 融合微流控和光子学
- 批准号:
0846489 - 财政年份:2009
- 资助金额:
$ 100万 - 项目类别:
Continuing Grant
Colaborative Research SST: Integration of Spectroscopic Sensors and Electroactive Nanowell Arrays with Microfluidic Chips Based on Thermocapillary Actuation
合作研究SST:光谱传感器和电活性纳米井阵列与基于热毛细管驱动的微流控芯片的集成
- 批准号:
0529045 - 财政年份:2005
- 资助金额:
$ 100万 - 项目类别:
Standard Grant
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